Manchester United fought back to defeat Bournemouth 2-1 on the road, with Marcus Rashford scoring a late winner in the Premier League on Saturday.
Arsenal and Liverpool could not be separated at the Emirates Stadium in a 1-1 draw.
Leicester City earned an emotional 1-0 victory over Cardiff City in south Wales following the death of owner Vichai Srivaddhanaprabha in a helicopter crash on October 27.
West Ham United ran out 4-2 winners against Burnley in the capital, while a rare victory for Newcastle United was greeted with joy at St James' Park, with the Magpies winning 1-0 against Watford.
Everton had an easy day at the office, claiming a 3-1 win over Brighton & Hove Albion at Goodison Park.
Tottenham Hotspur beat Wolverhampton Wanderers 3-2 in the late-evening match.
Here are Saturday's results and the season's top scorers:
Bournemouth 1-2 Manchester United
Cardiff City 0-1 Leicester City
Everton 3-1 Brighton & Hove Albion
Newcastle United 1-0 Watford
West Ham United 4-2 Burnley
Arsenal 1-1 Liverpool
Wolves 2-3 Spurs
Premier League Table (Games Played, Goal Difference and Points)
1. Liverpool 11, 16, 27
2. Manchester City: 10, 24, 26
3. Chelsea: 10, +17, 24
4. Spurs: 11, 9, 24
5. Arsenal: 11, 11, 23
6. Bournemouth: 11, 6, 20
7. Manchester United: 11, 1, 20
8. Watford: 11, 3, 19
9. Everton: 11, 4, 18
10. Leicester 11, 1, 16
11. Wolves: 11, -1, 15
12. Brighton: 10, -4, 14
13. West Ham: 11, -4, 11
14. Crystal Palace: 9, -6, 7
15. Burnley: 11, -13, 8
16. Southampton: 10, -8, 7
17. Newcastle: 11, -7, 6
18. Cardiff City: 11, -15, 5
19. Fulham: 10, -17, 5
20. Huddersfield: 10, -17, 3
Top Scorers (Player, Club and Goals, per the league's official website)
Pierre-Emerick Aubameyang, Arsenal: 7
Eden Hazard, Chelsea: 7
Sadio Mane, Liverpool: 6
Richarlison, Everton: 6
Sergio Aguero, Manchester City: 6
Callum Wilson, Bournemouth: 6
Glenn Murray, Brighton & Hove Albion: 6
Mohamed Salah, Liverpool: 5
Aleksandar Mitrovic, Fulham: 5
Roberto Pereyra, Watford: 5
Marko Arnautovic, West Ham: 5
Alexandre Lacazette, Arsenal, 5
A poor first half did not stop Manchester United taking the points on the south coast after Rashford smashed home the winner.
Callum Wilson gave Bournemouth an 11th-minute lead after United's defence fell asleep, and the visitors were off the pace. But Anthony Martial grabbing an equaliser after 35 minutes following excellent work by Alexis Sanchez, and Mourinho's side were a different team after the restart.
United turned the screw as the game progressed, and Rashford, Sanchez and Martial linked well in the absence of the injured Romelu Lukaku.
Martial in particular has hit top form, and his goal was his fifth in the last five games in all competitions.
The Red Devils claimed the points at the death when Rashford met a delicious Paul Pogba cross and lashed home from close range in the second minute of stoppage time.
Per Mark Mitchener of BBC Sport, Mourinho said: "The score should have been like 6-2. We were defensively awful. As a team, we didn't press or do any of the work we did in the week. People watching this game will not believe how hard we worked this week."
Rashford celebrated his strike on Twitter:
Liverpool nearly did enough to beat Arsenal in the capital, but the hosts earned a deserved point late in the day.
James Milner's strike on the hour mark gave the Reds the lead, but France international Lacazette sent the Gunners supporters wild with eight minutes remaining, finishing his fifth of the league season in style in a compelling encounter.
Squawka Football highlighted the hosts' dominance in possession:
Demarai Gray scored the only goal of the game at Cardiff as Leicester claimed three points after the tragic helicopter crash that killed chairman Srivaddhanaprabha.
There was a huge emotional outpouring when Gray netted after 55 minutes, with Foxes fans paying their respects to their beloved chairman.
Elsewhere, West Ham skipped past Burnley with ease as Felipe Anderson grabbed a brace and Marko Arnautovic scored his fifth of the season in the Premier League.
Johann Berg Gudmundsson equalised on the stroke of half-time, but Anderson's second-half double took the match away from the visitors. Burnley striker Chris Woods' 77th-minute header made it 2-2, but Javier Hernandez netted the killer blow during stoppage time.
Two goals by Richarlison helped Everton to a 3-1 over Brighton. Lewis Dunk equalised after 33 minutes for the Seagulls, but Seamus Coleman's strike shortly after half-time was the winning effort.
Newcastle finally had something to celebrate after Ayoze Perez's strike earned the hosts a 1-0 win against Watford.
Erik Lamela and Lucas Moura scored to give Spurs a commanding lead in the first half at Wolves, and Harry Kane's finish in the 61st minute appeared to have ended the contest.
However, the home team played with heart and conviction, and two penalty strikes made it an uncomfortable finale for the north Londoners.
Ruben Neves and Raul Jimenez both converted from the spot in the second half, but Spurs hauled themselves over the line.