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New England Patriots quarterback Tom Brady shouts as he runs onto the field before an NFL football game against the Denver Broncos on Sunday, Nov. 2, 2014, in Foxborough, Mass. (AP Photo/Elise Amendola)
New England Patriots quarterback Tom Brady shouts as he runs onto the field before an NFL football game against the Denver Broncos on Sunday, Nov. 2, 2014, in Foxborough, Mass. (AP Photo/Elise Amendola)Elise Amendola/Associated Press

Week 12 NFL Picks: Tips for Vegas Odds and Over/Under Score Predictions

Rob GoldbergNov 28, 2015

Just in case you didn't get enough turkey and football on Thanksgiving, you can spend all day Sunday watching more games and eating your leftovers, with 12 more contests in Week 12.

The first few games of the weekend featured some surprises, something that could continue throughout the rest of the slate. Although the outcomes aren't always predictable, the totals are a little easier to guess based on what we have seen recently.

With that in mind, here is a look at predictions for the week and a breakdown of the best over/unders.

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Buffalo Bills14-16Kansas City ChiefsBUF +7Under 41.5
Minnesota Vikings20-17Atlanta FalconsEVENUnder 45.5
Tampa Bay Buccaneers28-27Indianapolis ColtsTB +2.5Over 46.5
St. Louis Rams10-24Cincinnati BengalsCIN -10Under 42
Miami Dolphins13-20New York JetsNYJ -4Under 43
San Diego Chargers24-31Jacksonville JaguarsJAX -5Over 47
New York Giants30-21Washington RedskinsNYG -2.5Over 47.5
Oakland Raiders17-20Tennessee TitansEVENUnder 44
New Orleans Saints31-38Houston TexansHOU -3Over 48
Arizona Cardinals34-13San Francisco 49ersARI -11.5Over 45
Pittsburgh Steelers21-20Seattle SeahawksPIT +3.5Under 46
New England Patriots24-23Denver BroncosDEN +2.5Over 43.5
Baltimore Ravens17-21Cleveland BrownsCLE -3Under 41

Top Over/Under Picks

Buffalo Bills at Kansas City Chiefs (Under 41.5)

The Buffalo Bills have struggled with consistency this year, as injuries have been a big part of the season, but they showed last week the defense can be elite. The group held Tom Brady and the New England Patriots to their worst performance of the season in a 20-13 loss.

The key last game was the blitz to create problems for the quarterback, as noted by ESPN's Ed Werder:

If the front seven can get to Alex Smith, it could create a lot more problems in Week 12.

Meanwhile, the Kansas City Chiefs have been as good as anyone defensively over the past few weeks. They have averaged just 12.2 points allowed over the past six games, including just three to the San Diego Chargers in Week 11. The pass rush has been dominant, while Eric Berry has anchored the secondary into a formidable unit.

Neither team is going to have a lot of room to work with offensively in this game, and a few plays in either direction will likely decide it. In either case, there won't be a lot of points.

Minnesota Vikings at Atlanta Falcons (Under 45.5)

The Atlanta Falcons got off to a hot start this season, but the offense has not done its job lately. The squad hasn't scored more than 21 points in any of the last five games, resulting in four losses during that stretch.

After three interceptions last game, Matt Ryan is under a lot of pressure to turn things around. Unfortunately, the quarterback knows the upcoming matchup against the Minnesota Vikings defense will not be easy, per Craig Peters of Vikings.com:

"

I think on the whole, this is an outstanding defense. They tie-in well, the front end and back end. Their scheme allows them to play very aggressive and they’re very sound in what they do. I’ve been very impressed with them when you watch them on film. 

You certainly take a look at as much as you possibly can and try and have yourself prepared for their entire package, but you also have to be able to adjust in game. It comes down to us being on top of our scheme and understanding what we need to do offensively, regardless of what they throw at us.

"

Although the Green Bay Packers were able to get the better of the Vikings defense last week, the unit has still been among the best in the NFL this year, allowing the third-fewest points in football. With Devonta Freeman out with a concussion, per Tiffany Blackmon of NFL Network, the Falcons will really struggle to move the football.

The Falcons defense has done its job as well in recent weeks and should be able to limit the Vikings through the air, which should also contribute to a low-scoring battle between these teams.

Arizona Cardinals at San Francisco 49ers (Over 45)

The last two games likely quieted any remaining doubters of the Arizona Cardinals. They beat the Seattle Seahawks in a place few road teams ever win at and followed that up with an impressive win against the Cincinnati Bengals. They had huge offensive showings against two of the better defenses in football and scored a combined 73 points in the two games.

Bob McManaman of the Arizona Republic noted how good the offense has been this year:

Considering what this group did against the Bengals and Seahawks, you can believe it will have little problem torching the struggling San Francisco 49ers defense.

Although the 49ers offense hasn't been great this year, Blaine Gabbert has at least done a better job than Colin Kaepernick of taking care of the football. The squad has had no turnovers in the last two games, and that could help do enough to get a few points onto the scoreboard.

Of course, if the Cardinals want, they might be able to reach this total on their own. 

Odds courtesy of Odds Shark. Follow Rob Goldberg on Twitter for more year-round sports analysis. 

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