Pro Football 101 Week One NFL Fantasy Rankings: Quarterbacks

Must Starts

1. Tom Brady vs. Buffalo Bills

Brady returns to the gridiron to face the Buffalo Bills on Monday Night. And while the Bills possess a pretty solid young defense, in the end, it will not matter.

Brady will come out slinging and easily eclipse the three hundred yard mark with at least three TDs. The Brady to Moss show should be in full effect under the bright lights and he tops this week's QB fantasy rankings.

Jim Schwartz was a heck of a defensive coordinator in his time with the Titans. Unfortunately he wasn't able to bring his players along to Detroit—because while they should be improved, they'll prove no match for Brees and his explosive offense.

Look for Brees to pick this secondary apart and to easily surpass the 300-yard mark with three TDs.

The Raiders pass defense is actually one of their strong points, but star CB Nnadi Asomugha is out with an injury—although he says he'll be back in time for Week One.

Regardless, the Chargers are a team that's built through the air. Look for Rivers to take advantage of Jackson and Gates, along with Sproles on dumps out of the backfield, to eclipse 250 yards with at least three TDs.

Nothing has happened in the offseason to suggest the Broncos will be any better on defense in 2009. On the other hand, the Bengals possess a solid offense with the return of Carson Palmer, and the offseason signing of Laveurnes Coles to take over as the No. 2 receiver gives them a solid trio of receivers. And oh yeah, Chad Ochocinco is motivated once again.

Look for a big day from Palmer with 250 yards and two to three TDs.

Although Baltimore's expected to feature more of a running offense this season, the Chiefs are weak defensively. And Flacco will have many opportunities to attack through the air and find his TE and receivers in favorable matchups.

A great fantasy sleeper if your regular starter has a poor matchup.

With the addition of T.O., the Bills are expected to be more dangerous on offense, and the Patriots still need to show that the offseason upgrades in the secondary will pan out. The Bills should also be playing from behind in this one—so expect a lot of passing opportunities for Edwards.

Playing at home and coming off the Super Bowl appearance, the Cardinals should be pretty amped up. And the Niners don't possess a formidable pass rush, which means that Warner will have time to locate his outstanding receiving targets for what should be a big day through the air.

The Aaron Rodgers Show is in full effect this season, and all of the pieces are in place for a very potent offense. The Bears secondary was its weak link last year and we like for Green Bay to attack this unit heavily. Look for 250 yards and two TDs.

Although Favre isn't fully acclimated to his new offense in Minnesota, Cleveland certainly doesn't present much of a defensive challenge in Week One. When not handing the ball off to superstar runner Adrian Peterson, look for Favre to locate—and hit—his weapons (Berrian, Harvin, Schiancoe) all day long.