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College Football 2024: Week 5 Predictions for Every Game

David KenyonSep 26, 2024

For very good reason, the clash between No. 2 Georgia and No. 4 Alabama is the biggest story of Week 5. The winner of that SEC showdown will basically be penned into the College Football Playoff.

But that is simply one massive game on a great weekend.

Oklahoma State and Kansas State, both coming off a loss, are ready for a battle of early survival in the Big 12. Penn State hosts Illinois in a matchup of unbeaten Big Ten teams, and Louisville travels to Notre Dame for a contest with significant value in the CFP race.

More than a handful of other Top 25 programs are hitting the road for a conference game, too. It's a busy slate around the nation.

Along with a preview of each ranked team, we've predicted every game involving a Football Bowl Subdivision school.

AP Nos. 25-21

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Jake Retzlaff
Jake Retzlaff

Washington State (4-0) at No. 25 Boise State (2-1), 10 p.m. ET

Wazzu has quietly put together a 4-0 start with triumphs over Texas Tech and Washington. Boise State, meanwhile, gave Oregon a real scare in Week 2. If you're able to stay up late, it's worth the watch. I'll lean Boise because of star running back Ashton Jeanty and home-field advantage in what presumably will be a high-scoring affair.

Prediction: Boise State 38, Washington State 33


Arkansas (3-1) vs. No. 24 Texas A&M (3-1), 3:30 p.m. ET (in Arlington)

The victory at Auburn was an enormous boost to Arkansas' hopes of making a bowl. However, the Hogs' remaining slate is a monster—six of their eight opponents are currently ranked—and that stretch begins with a neutral-site clash. Texas A&M quarterback Conner Weigman will be a game-time decision, but Marcel Reed has been a capable replacement while getting plenty of help from the defense.

Prediction: Texas A&M 27. Arkansas 22


No. 20 Oklahoma State (3-1) at No. 23 Kansas State (3-1), Noon ET

For prediction, see No. 20 Oklahoma State.


No. 22 BYU (4-0) at Baylor (2-2), Noon ET

Apologies for ignoring my brain last week, BYU. It won't happen again. The early kickoff is a slight cause for hesitation, but a sturdy defense should be enough for the unbeaten Cougars on the road.

Prediction: BYU 28, Baylor 20


No. 21 Oklahoma (3-1) at Auburn (2-2), 3:30 p.m. ET

Oklahoma is benching Jackson Arnold in favor of Michael Hawkins Jr., and Auburn's QB situation is also a disaster with a back-and-forth between Payton Thorne and Hank Brown. Both teams have quality defenses, so it'll probably be a low-scoring slog—one that could go either way.

Prediction: Oklahoma 20, Auburn 16

AP Nos. 20-16

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Jaylin Noel
Jaylin Noel

No. 20 Oklahoma State (3-1) at No. 23 Kansas State (3-1), Noon ET

Oklahoma State lost at home to a backup quarterback, and Kansas State laid an egg on the road. Neither team is entering this conference tilt on a positive note. For me, though, the greatest concern is OSU's complete lack of a running game despite bringing back the entire offensive line (and more!) in front of Ollie Gordon II. Until that changes, I'll struggle to pick the Pokes in a competitive game.

Prediction: Kansas State 26, Oklahoma State 20


No. 19 Illinois (4-0) at No. 9 Penn State (3-0), 7:30 p.m. ET

For prediction, see No. 9 Penn State.


No. 18 Iowa State (3-0) at Houston (1-3), 7 p.m. ET

Through four weeks, Houston has mustered just 4.8 yards per snap. That's not an encouraging sign opposite Iowa State, which has yielded only 9.7 points per game in three victories so far.

Prediction: Iowa State 31, Houston 13


Stanford (2-1) at No. 17 Clemson (2-1), 7 p.m. ET

Last weekend, Stanford traveled to Syracuse and stole a Friday night win. Great result for the Cardinal in their ACC opener. Another cross-country trip is on the docket, however, and Clemson will be a more formidable opponent. The main story is whether Clemson QB Cade Klubnik will continue a hot streak as the Tigers work to rebuild their national perception after the rough loss to Georgia.

Prediction: Clemson 44, Stanford 21


No. 15 Louisville (3-0) at No. 16 Notre Dame (3-1), 3:30 p.m. ET

For prediction, see No. 15 Louisville.

AP Nos. 15-11

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Kalel Mullings
Kalel Mullings

No. 15 Louisville (3-0) at No. 16 Notre Dame (3-1), 3:30 p.m. ET

Can the Notre Dame defense keep carrying the team? Transfer quarterback Riley Leonard has trudged to 5.7 yards per attempt and topped out 163 passing yards in his first four appearances with the Fighting Irish. The hosts are favored, but Louisville—which has given up a meager 2.5 yards per carry—is built to beat ND for a second straight year if Leonard isn't more effective as a passer.

Prediction: Louisville 23, Notre Dame 19


South Alabama (2-2) at No. 14 LSU (3-1), 7:45 p.m. ET

Losing star linebacker Harold Perkins Jr. to a season-ending knee injury will be problematic for LSU later on. This weekend, it shouldn't be a big issue. Given that South Alabama has scored 135 points in the last two games and LSU is dealing with a habit of slow starts, this matchup could be a little more uncomfortable than expected for the hosts.

Prediction: LSU 45, South Alabama 24


Wisconsin (2-1) at No. 13 USC (2-1), 3:30 p.m. ET

Similarly, the Badgers are regrouping after a serious knee injury to quarterback Tyler Van Dyke. Braedyn Locke has some experience, but he's averaged only 5.1 yards per attempt in scattered snaps for Wisconsin. It's a tough sell to predict an upset at USC.

Prediction: USC 27, Wisconsin 13


Minnesota (2-2) at No. 12 Michigan (3-1), Noon ET

Relative to Big Ten and CFP aspirations, the absence of a threatening passing game is not sustainable for Michigan. But, hey, Minnesota ceded 272 rushing yards and only 62 through the air in last weekend's 31-14 loss to Iowa. Michigan can bully-ball its way to another win.

Prediction: Michigan 34, Minnesota 16


No. 11 Missouri (4-0), Idle

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AP Nos. 10-6

4 of 7
Dillon Gabriel
Dillon Gabriel

Arizona (2-1) at No. 10 Utah (4-0), 10:15 p.m. ET

I have no idea if Cameron Rising will return. He's cleared to play, but the Utah coaching staff needs to see the QB throw with adequate velocity to start him. So, that's the latest. Despite the uncertainty around him, I'll continue tossing darts in Utah's favor because of a defense that has surrendered no more than 21 points so far.

Prediction: Utah 24, Arizona 20


No. 19 Illinois (4-0) at No. 9 Penn State (3-0), 7:30 p.m. ET

The simple version is Penn State has a better offense, better defense and is playing at home. But if the Illini can generate a few takeaways—and they already have 10 this season, tied for the fifth-highest total in the nation—that's the key to flipping the result.

Prediction: Penn State 27, Illinois 19


No. 8 Oregon (3-0) at UCLA (1-2), 11 p.m. ET

UCLA hasn't scored more than 17 points in a game this season. Safe to say the Bruins are a hefty underdog here, especially after Oregon finally had a strong all-around performance last time out.

Prediction: Oregon 41, UCLA 17


Virginia Tech (2-2) at No. 7 Miami (4-0), Friday, 7:30 p.m. ET

In losses to Vanderbilt and Rutgers, Virginia Tech allowed 11.2 yards per pass attempt. Those offenses have nowhere near the firepower of Miami's aerial attack, so there may be plenty of nerves in Blacksburg this week. Rivalries can get weird, but Miami should be able to pull away eventually.

Prediction: Miami 37, Virginia Tech 23


Kentucky (2-2) at No. 6 Ole Miss (4-0), Noon ET

Which version of Kentucky will show up? After a blowout loss to South Carolina, the Wildcats—one week later and in the same building—nearly beat Georgia. While I'm taking Ole Miss regardless, you could make a convincing case for a lopsided result or a close finish.

Prediction: Ole Miss 38, Kentucky 21

AP Nos. 5-1

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Carson Beck
Carson Beck

No. 5 Tennessee (4-0), Idle


No. 3 Ohio State (3-0) at Michigan State (3-1), 7 p.m. ET

Ohio State, interestingly enough, hasn't lost in East Lansing since 1999. There is little reason to believe that streak won't reach 10 straight for the Buckeyes, given the combination of their defensive strength and Michigan State's growing pains on offense.

Prediction: Ohio State 45, Michigan State 17


No. 2 Georgia (3-0) at No. 4 Alabama (3-0), 7:30 p.m. ET

One of the best matchups on the 2024 calendar, Georgia heads to Tuscaloosa for only the third regular-season clash between the powerhouses in the last decade. We know it'll be a slugfest. We know Jalen Milroe's mobility will be vital for Bama's chances. We know UGA's defense is sensational. If you prefer the Tide, I'd nod in understanding. I just happen to trust Georgia by the slightest of margins, not in the least because of head coach Kirby Smart.

Prediction: Georgia 24, Alabama 23


Mississippi State (1-3) at No. 1 Texas (4-0), 4:15 p.m. ET

No matter if Quinn Ewers or Arch Manning starts for Texas this weekend, the Longhorns will be a heavy favorite. Mississippi State gave up 86 combined points in recent home losses to Toledo and Florida.

Prediction: Texas 48, Mississippi State 21

Rest of the Slate, Part I

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RJ Harvey
RJ Harvey

Army (3-0) at Temple (1-3), Thursday, 7:30 p.m. ET
Prediction: Army 35, Temple 14

Washington (3-1) at Rutgers (3-0), Friday, 8 p.m. ET
Prediction: Rutgers 30, Washington 24

Western Kentucky (3-1) at Boston College (3-1), Noon ET
Prediction: Boston College 27, WKU 20

Northern Illinois (2-1) at North Carolina State (2-2), Noon ET
Prediction: NC State 21, NIU 16

Holy Cross (1-3) at Syracuse (2-1), Noon ET
Prediction: Syracuse 48, Holy Cross 10

Maryland (3-1) at Indiana (4-0), Noon ET
Prediction: Indiana 31, Maryland 26

Nebraska (3-1) at Purdue (1-2), Noon ET
Prediction: Nebraska 34, Purdue 20

Navy (3-0) at UAB (1-2), Noon ET
Prediction: Navy 31, UAB 21

South Florida (2-2) at Tulane (2-2), Noon ET
Prediction: Tulane 38, USF 24

Buffalo (3-1) at Connecticut (2-2), Noon ET
Prediction: Buffalo 28, UConn 23

Ball State (1-2) at James Madison (3-0), 1:30 p.m. ET
Prediction: JMU 45, Ball State 24

Texas State (2-1) at Sam Houston (3-1), 3 p.m. ET
Prediction: Texas State 34, Sam Houston 27

Louisiana (2-1) at Wake Forest (1-2), 3:30 p.m. ET
Prediction: Wake Forest 33, Louisiana 20

TCU (2-2) at Kansas (1-3), 3:30 p.m. ET
Prediction: TCU 38, Kansas 30

Colorado (3-1) at UCF (3-0), 3:30 p.m. ET
Prediction: UCF 41, Colorado 28

Liberty (4-0) at Appalachian State (2-2), 3:30 p.m. ET
Prediction: Liberty 36, App State 27

Akron (1-3) at Ohio (2-2), 3:30 p.m. ET
Prediction: Ohio 28, Akron 17

Eastern Michigan (3-1) at Kent State (0-4), 3:30 p.m. ET
Prediction: EMU 35, Kent State 16

San Diego State (1-2) at Central Michigan (2-2), 3:30 p.m. ET
Prediction: CMU 24, SDSU 19

Western Michigan (1-2) at Marshall (1-2), 3:30 p.m. ET
Prediction: Marshall 30, WMU 24

Massachusetts (1-3) at Miami (Ohio) (0-3), 3:30 p.m. ET
Prediction: Miami 31, UMass 14

Fresno State (3-1) at UNLV (3-0), 3:30 p.m. ET
Prediction: Fresno State 29, UNLV 23

Georgia Southern (2-2) at Georgia State (2-1), 3:30 p.m. ET
Prediction: Georgia State 37, Georgia Southern 31

Rest of the Slate, Part II

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Behren Morton
Behren Morton

North Carolina (3-1) at Duke (4-0), 4 p.m. ET
Prediction: Duke 34, UNC 27

UTSA (2-2) at East Carolina (2-2), 4 p.m. ET
Prediction: UTSA 31, ECU 23

Old Dominion (0-3) at Bowling Green (1-2), 5 p.m. ET
Prediction: Bowling Green 30, ODU 17

Wagner (2-2) at Florida Atlantic (1-3), 6 p.m. ET
Prediction: FAU 38, Wagner 14

Louisiana Tech (1-2) at Florida International (1-3), 6 p.m. ET
Prediction: Louisiana Tech 26, FIU 21

UT Martin (1-3) at Kennesaw State (0-3), 6 p.m. ET
Prediction: Kennesaw State 34, UT Martin 17

Tulsa (2-2) at North Texas (3-1), 7 p.m. ET
Prediction: North Texas 42, Tulsa 34

Charlotte (1-3) at Rice (1-3), 7 p.m. ET
Prediction: Rice 28, Charlotte 20

Louisiana-Monroe (2-1) at Troy (1-3), 7 p.m. ET
Prediction: Troy 31, ULM 21

Middle Tennessee (1-3) at Memphis (3-1), 7:30 p.m. ET
Prediction: Memphis 45, MTSU 28

Florida State (1-3) at SMU (3-1), 8 p.m. ET
Prediction: SMU 27, Florida State 24

Cincinnati (3-1) at Texas Tech (3-1), 8 p.m. ET
Prediction: Texas Tech 35, Cincinnati 27

New Mexico (0-4) at New Mexico State (1-3), 8 p.m. ET
Prediction: New Mexico 30, NMSU 23

Air Force (1-2) at Wyoming (0-4), 8 p.m. ET
Prediction: Air Force 28, Wyoming 14

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