Kentucky Derby 2022 Contenders: Final Vegas Odds and Projections for Top Horses

Kristopher Knox@@kris_knoxFeatured ColumnistMay 7, 2022

Kentucky Derby 2022 Contenders: Final Vegas Odds and Projections for Top Horses

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    Kentucky Derby Day is here, race fans! The 148th running of the Derby is set to take place on Saturday evening, and an afternoon of mint juleps, flashy suits, fancy hats and festivities will precede it.

    The race itself is shaping up to be a great one, with a few early favorites but no overwhelming top pick. Epicenter and Taiba shifted to the final favorites on Friday evening, but Zandon, Messier and Mo Donegal aren't far behind.

    Ethereal Road, who was set to run from the No. 20 post, was scratched on Friday and replaced by Rich Strike.

    One of the 20 horses in the field is going to go on to chase the Triple Crown in the Preakness Stakes and perhaps the Belmont. Below, you'll find a look at the final Vegas odds heading into race day—though they will evolve up until start time—complete race information and predictions for the top finishers.

148th Kentucky Derby

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    Horsephotos/Getty Images

    Where: Churchill Downs in Louisville, Kentucky

    When: Saturday, May 7

    Time: 6:57 p.m. ET

    TV and Live Stream: NBC,, NBC Sports App and Peacock

    Qualification: Three-year-old thoroughbreds

    Prize Money: $3 million purse ($1.86 million payout to the winner)

Latest Vegas Odds

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    Andy Lyons/Getty Images

    Taiba 5-1

    Epicenter 5-1

    Messier 7-1

    Mo Donegal 7-1

    Zandon 8-1

    White Abarrio 11-1

    Charge It 12-1

    Smile Happy 14-1

    Cyberknife 15-1

    Crown Pride 17-1

    Happy Jack 22-1

    Tiz the Bomb 25-1

    Zozos 39-1

    Barber Road 41-1

    Simplification 42-1

    Summer Is Tomorrow 44-1

    Pioneer of Medina 51-1

    Tawny Port 65-1

    Classic Causeway 68-1

    Rich Strike 99-1


    *Odds via the official Kentucky Derby website and accurate as of Saturday morning.


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    Andy Lyons/Getty Images

    Picking a winner out of this year's field is tricky, especially with rainy and muddy conditions likely. Mild temperatures and possible showers are in the forecast, which could heavily impact the race.

    "Every horse is different and depends on a case-by-case scenario, but jockeys sometimes change horses' hooves on Derby day to accommodate the cold, rain, or muddy track," Wes Peterson of Ocala Breeders said, per Jordan Smith of Fox Weather (h/t the New York Post). "It is a game-time decision, if you will, as the weather can change in a hurry."

    A sloppy track could allow one of the long shots to steal the glory on Saturday, though banking on that outcome would be unwise. It would, however, be smart to follow track conditions throughout the day. Horses like Tawny Port and Classic Causeway are long shots for a reason, they're unlikely to win.

    I'm not sold on Friday favorite Taiba, either. The Tim Yakteen-trained colt lacks big-time racing experience, starting but winning only two career races. Taiba's team could carry some momentum from last month's win at the Santa Anita Derby—which is a 1⅛-mile track—but this is still a largely untested horse.

    Look for the surging and more experienced Epicenter to fare better in a crowded field. The Steven Asmussen-trained colt has won five of his last six races, including a Grade 2 win at the Louisiana Derby in March.

    Asmussen is thrilled about his chances of winning a career-first Derby.

    "We're Derby dreamers, for him to have checked off all the boxes, the buildup, exciting, representing central Kentucky, the fanbase everywhere, wonderful horses of this quality, to excited people, we're just proud to be in this position," Asmussen said of Epicenter, per WLKY Kentucky.

    Epicenter has a favorable inside draw (post No. 3), as does Messier, another Yakteen horse. Messier, who will run from the No. 7 post, is coming off a second-place finish in the Santa Anita Derby. Both Messier and Taiba (No. 12 post) were previously trained by Bob Baffert—who is serving a two-year ban from Churchill Downs for horse doping.

    "I think no matter how those horses run, they'll be Bob's," fellow trainer D. Wayne Lukas said, per John Cherwa of the Los Angeles Times. "Now, the general public, a lot of them, won't know the difference. [But] all the horse people will know they are Bob's."

    Smile Happy, who will break from the No. 3 gate, is a long shot worth following. The Kenneth McPeek-trained colt has two second-place finishes this season—behind Epicenter and Zandon—but won the Grade 2 Kentucky Jockey Club race at Churchill Downs in November.

    A strong inside start could give Smile Happy a shot at the upset, especially if a wet track negates his limited closing speed.


    Top-Five Predictions

    1. Epicenter

    2. Messier

    3. Zandon

    4. Taiba

    5. Smile Happy