The Argentinian has only ever played first-team football at Barca, while Ronaldo is at the fourth club of his senior career following his summer move from Real Madrid to Juve.
"No, maybe he misses me. I played in England, Spain, Italy, Portugal, in the national team, while he is still in Spain. Maybe he needs me more. For me, life is a challenge, I like it, and I like to make people happy. I would like him to come to Italy one day. Like me, accept the challenge. However, if he is happy there, I respect him. He is a fantastic player, a good guy, but I do not miss anything here. This is my new life, and I'm happy."
Ronaldo, 33, began his career at Sporting Lisbon before moving to Manchester United in 2003.
He became a superstar at Old Trafford, winning three Premier League titles and the 2007-08 UEFA Champions League.
An £80 million move to Real in 2009 then saw him come into direct competition with Messi in La Liga, and he won two more league titles and four more Champions Leagues at the Santiago Bernabeu.
After five months at Juve, the Portuguese is well on his way to another domestic title—the Old Lady are eight points clear at the top of Serie A.
And he said he is happy at his new club, per Tuttosport (h/t Calciomercato): "I am happy here, the city is cool, different and smaller than Madrid but I like it. The fans are amazing and the players are good: they’re humble and they like to work hard. We are like a family, it’s all great."
Juve and Barcelona have both qualified for the knockout rounds of the 2018-19 Champions League, so there is a chance Messi and Ronaldo could meet this season despite no longer being in the same league.
It would be a thrilling prospect to see Messi, 31, ply his trade in another league after 17 years at Barca—he joined their youth academy aged 13.
But he has a contract at the Camp Nou through to 2021 and has rarely given any indication of a desire to depart the Blaugrana.