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Chelsea's Portuguese manager Jose Mourinho (L) and Arsenal's French manager Arsene Wenger (R) watch from the side during the FA Community Shield football match between Arsenal and Chelsea at Wembley Stadium in north London on August 2, 2015. AFP PHOTO / GLYN KIRK

 -- NOT FOR MARKETING OR ADVERTISING USE / RESTRICTED TO EDITORIAL USE --        (Photo credit should read GLYN KIRK/AFP/Getty Images)
Chelsea's Portuguese manager Jose Mourinho (L) and Arsenal's French manager Arsene Wenger (R) watch from the side during the FA Community Shield football match between Arsenal and Chelsea at Wembley Stadium in north London on August 2, 2015. AFP PHOTO / GLYN KIRK -- NOT FOR MARKETING OR ADVERTISING USE / RESTRICTED TO EDITORIAL USE -- (Photo credit should read GLYN KIRK/AFP/Getty Images)GLYN KIRK/Getty Images

Premier League Fixtures: Week 12 Schedule, Score Predictions for EPL Matchday

Stuart NewmanNov 14, 2016

One of the most bitter rivalries in English football takes centre stage to kick off Week 12 of the 2016/17 Premier League, as Manchester United take on Arsenal at Old Trafford.

The early kick-off of the week will see Jose Mourinho and Arsene Wenger lock horns once again, and it’s safe to say the former will be looking forward to meeting his old adversary again.

The Manchester United boss has never been on the losing side when opposite Wenger’s dugout, but can he keep that record up with his new side?

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Here we look ahead to the key Week 12 fixture and predict how the rest of the matches could play out.

Arsenal have started the 2016/17 campaign in fine fettle and finally look worthy of a serious title challenge, but they haven’t yet been given a thorough examination of their table-topping credentials.

Even when title rivals Chelsea visited the Emirates Stadium back in September, the Blues were out of sorts and were completely outdone by the Gunners.

Now, though, Arsenal must do battle with a team that aren’t strangers to sobering up their dreams of silverware.

DateTime (GMT)FixturePrediction
Saturday November 1912:30 p.m.Manchester United vs. Arsenal2-1
Saturday November 193 p.m.Sunderland vs. Hull City2-1
Saturday November 193 p.m.Watford vs. Leicester City0-1
Saturday November 193 p.m.Crystal Palace vs. Manchester City1-3
Saturday November 193 p.m.Everton vs. Swansea City2-2
Saturday November 193 p.m.Stoke City vs. AFC Bournemouth1-1
Saturday November 193 p.m.Southampton vs. Liverpool1-3
Saturday November 195:30 p.m.Tottenham Hotspur vs. West Ham United4-0
Sunday November 204 p.m.Middlesbrough vs. Chelsea0-1
Monday November 218 p.m.West Brom vs. Burnley1-1

Just nine months ago, Manchester United dealt the Gunners a crushing blow in their pursuit of the 2015/16 title when Marcus Rashford starred in a 3-2 win for the Red Devils.

United were forced to field a makeshift lineup after several injuries left them with a depleted squad, but they still managed to see off Wenger’s hapless side.

SWANSEA, WALES - NOVEMBER 06:  Matteo Darmian of Manchester United (L) Zlatan Ibrahimovic of Manchester United (C) and Jesse Lingard of Manchester United (R) celebrate victory during the Premier League match between Swansea City and Manchester United at L

That win was United’s seventh in their last nine league games at Old Trafford against Arsenal, according to 11v11. In fact, the Gunners haven’t picked up all three points at the Theatre of Dreams since way back in 2006 when Emmanuel Adebayor struck late.

Both United and Arsenal look in excellent form going in to Saturday’s match, with both front lines proving incredibly dangerous of late. We could well be in for another thriller between the pair.

Elsewhere, league leaders Liverpool face a tricky-looking trip to Southampton at 3 p.m. (GMT) on Saturday, with the Reds looking to keep their heads above the chasing pack.

The Saints’ home form has been exemplary of late, although they were defeated 2-0 by Chelsea back in Week 10.

Pep Guardiola’s Manchester City travel to Crystal Palace at the same time on Saturday, before Tottenham Hotspur take on London rivals West Ham United at White Hart Lane in the evening kick-off.

Chelsea, meanwhile, will need to produce a solid display to see off Middlesbrough at the Riverside Stadium on Sunday, as the Teesiders are looking more and more solid every week.

The 2016/17 Premier League is looking like a hugely exciting campaign, with no telling which of the big sides will end up on top.

If Arsenal are to get their name on the Premier League trophy again, then they need to do some damage at Old Trafford on Saturday, while United themselves won’t have given up on taking back their throne just yet and will go all out for victory.

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