Southern Miss vs. Nebraska: TV Info, Spread, Injury Updates, Game Time and More

No. 22 Nebraska hosts Southern Miss on Saturday in Lincoln after a harrowing 37-34 victory over Wyoming in Week 1.

In the nail-biter against the Cowboys, the Cornhuskers rattled off 375 rushing yards but also allowed Wyoming quarterback Brett Smith to pass for 383 yards and four touchdowns, while sophomore Shaun Wick scampered for 101 yards and a touchdown on just 12 carries.

Southern Miss lost its season opener against Texas State, 22-15. The Golden Eagles posted 400 yards of total offense but also committed six turnovers in the game. They also converted only 5 of 20 attempts on third down.

Here's a breakdown of the clash on Saturday, complete with my prediction.

When: Saturday, Sept. 7 at 6 p.m. ET

Where: Memorial Stadium, Lincoln, Neb.

Watch: Big Ten Network

Live Stream: BTN2GO

Betting Line (via Bovada): Nebraska -28

Southern Miss Injuries (via USA Today)

No injuries to report

Nebraska Injuries (via USA Today)

Taylor Martinez, QB, Probable (Shoulder)

Jake Cotton, OL, Questionable (Undisclosed)

Jared Afalava, LB, Undisclosed (Out)

Courtney Love, LB, Undisclosed (Out Indefinitely)

Kevin Williams, DT, Knee (Out for Season)

Top Storyline: Can Nebraska's Defense Hold Up This Season?

Nebraska may have defeated Wyoming on Saturday, but the young defense surrendered 602 total yards and 35 first downs. The Cowboys scored all five of their offensive touchdowns in less than two minutes.

This, against a team that went 4-8 (3-5 C-USA) last season and was ranked 101st in the nation by The Orlando Sentinel in the preseason.

While head coach Bo Pelini appeared to downplay the defensive performance after the game, defensive coordinator John Papuchis was not happy, calling the fourth quarter a "nightmare," according to Mitch Sherman of ESPN.com.

Southern Miss shot itself in the foot with turnovers against Texas State, but the fact that the Golden Eagles posted 400 total yards of offense still means they can be dangerous against Nebraska.

Prediction: Nebraska 40, Southern Miss 20

I simply can't see Nebraska playing as poorly on defense against Southern Miss as it did against Wyoming. You can bet Papuchis has been firing barbs at the defensive unit this week.

Nonetheless, this is nothing new for Nebraska. The Cornhuskers allowed 4.76 yards per carry last season, as well as 26 rushing touchdowns—both marks ranked 96th in the nation.

Of course, Southern Miss, while posting a lot of total yards against Texas State, did commit a plethora of turnovers. In the end, it was a poor offensive performance.

Nebraska should play better on defense while maintaining its powerful rushing attack.