NFL Week 11 Odds: Best Picks to Bet on Sunday's Schedule

Another week of NFL football means another opportunity for bettors to make some money.

The Week 11 slate is full of matchups that, on paper, aren't expected to be very competitive. For example, the San Francisco 49ers are favored by 12 points over the Tampa Bay Buccaneers, and the Miami Dolphins are favored by 13.5 points over the Las Vegas Raiders.

Bettors should probably stay away from spreads that large, but there are still some solid picks to be had this weekend.

That said, here's a look at some of the best bets on Sunday's slate. (All lines/odds via DraftKings Sportsbook).

Houston Texans (-6) Over Arizona Cardinals (-110)

Cooper Neill/Getty Images

HOUSTON, TX - NOVEMBER 05: C.J. Stroud #7 of the Houston Texans reacts after a play against the Tampa Bay Buccaneers during the second half at NRG Stadium on November 5, 2023 in Houston, Texas. (Photo by Cooper Neill/Getty Images)

Kyler Murray has returned to the lineup for the Arizona Cardinals after recovering from a torn ACL suffered during the 2022 season, but it's just too hard to bet against Houston Texans rookie quarterback C.J. Stroud right now.

Stroud is coming off two brilliant performances in wins over the Buccaneers and Cincinnati Bengals.

The Ohio State product set a rookie record with 470 passing yards against the Bucs in a 39-37 Week 9 victory. He also threw five touchdowns in that matchup.

In a 30-27 win over the Bengals in Week 10, Stroud threw for 356 yards and one touchdown against one interception, in addition to rushing for eight yards and one score.

Aside from Stroud's exceptional play, it's important to note he's going up against an Arizona defense that has struggled this year. The Cardinals are allowing 208.4 passing yards, 134.2 rushing yards and 26.3 points per game.

Even if Sunday's game were to turn into a shootout, backing Stroud and the Texans against a newly returned Murray and the Cardinals feels like a solid bet, especially considering Houston head coach DeMeco Ryans is very familiar with his opponent thanks to his time with the San Francisco 49ers.

Cleveland Browns vs. Pittsburgh Steelers Under 33 Points (-110)

Perry Knotts/Getty Images

PITTSBURGH, PA - NOVEMBER 12: Kenny Pickett #8 of the Pittsburgh Steelers runs out of the tunnel prior to an NFL football game against the Green Bay Packers at Acrisure Stadium on November 12, 2023 in Pittsburgh, Pennsylvania. (Photo by Perry Knotts/Getty Images)

This one isn't rocket science.

The Pittsburgh Steelers have one of the worst offenses in the NFL under offensive coordinator Matt Canada, who has been the subject of criticism throughout the season for the team's struggles moving the ball and putting points on the board.

Pittsburgh is averaging 180.3 passing yards, 103.2 rushing yards and just 17.3 points per game. Second-year quarterback Kenny Pickett has also been largely ineffective, and the likelihood of the offense getting anything going against one of the best defenses in the NFL in Cleveland is slim.

The Browns are allowing just 151.1 passing yards per game, which is the best mark in the NFL, 91.6 rushing yards per game and 18.9 points per game.

If the Browns had Deshaun Watson available, it would be reasonable to hammer the over, but the Cleveland offense is just as ineffective with the veteran quarterback sidelined.

Watson has been ruled out for the remainder of the year with a shoulder injury and rookie quarterback Dorian Thompson-Robinson is in line to get his second NFL start against the Steelers on Sunday.

Thompson-Robinson also started a Week 4 matchup against the Baltimore Ravens and the Browns failed to score a touchdown in that matchup, falling 28-3 as the rookie threw for just 121 yards and three interceptions.

As long as the line stays at more than 30 points, this feels like an easy pick for Sunday's slate.

Green Bay Packers (+3) Over Los Angeles Chargers (-112)

Perry Knotts/Getty Images

PITTSBURGH, PA - NOVEMBER 12: Jordan Love #10 of the Green Bay Packers warms up prior to an NFL football game against the Pittsburgh Steelers at Acrisure Stadium on November 12, 2023 in Pittsburgh, Pennsylvania. (Photo by Perry Knotts/Getty Images)

Jordan Love is mediocre, and the Green Bay Packers aren't very good, but there's a few reasons why the Cheeseheads can cover the spread on Sunday against Justin Herbert and the Los Angeles Chargers.

The Bolts are on the brink with a 4-5 record, and it's mainly due to their mediocre defense.

Los Angeles is allowing 291.2 passing yards, 102 rushing yards and 23.9 points per game.

So while Love has struggled this year, he shouldn't have a difficult time throwing and putting up points against Los Angeles on Sunday.

Additionally, Love has thrown for 225-plus yards in each of his last three games and is good for at least a few solid completions during each matchup. With the L.A. defense playing like it has, that's all the Packers may need on Sunday.

The Green Bay defense has also been decent this season, allowing 187.6 passing yards and 20.2 points per game. It won't be easy for the Packers to contain Herbert, but he likely won't have as easy of a time against Green Bay as some may think.

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