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On the WTA side of the tournament, there will be some pretty obvious names, and we'll kick it off with Serena Williams.
Serena has had a difficult couple of years, but it appears she is coming back into form. She suffered a foot injury and dropped all the way down to No. 175 in the world in 2011.
Since coming back from injury, however, Serena has won her past two tournaments and is now ranked 31st in the world.
Williams will obviously get a strong reception from the fans at Flushing Meadows as they are extremely patriotic at the US Open and always want to see one of their own take home the title.
This will be just the first appearance in the US Open since 2009 when Serena lost in the semifinals to Kim Clijsters. It was also in the 2009 US Open semifinal where Serena's infamous blow up occurred.
The umpire claims that Serena said "I am going to kill you," and Serena subsequently received a fine from the WTA; it was a dark spot on Williams 2009 season.
It should be interesting to see how Williams performs on center court at the US Open this year, but there is no doubt in the world that she is a fan favorite.