Missouri came into last Saturday's game against Colorado winning eight straight against the Buffs, including four straight triumphs at the Coors Event Center.
However, both of these streaks came to a crashing end as Colorado, behind sophomore guard Alec Burks, upended the stunned Tigers, 89-76.
Burks was the main reason why the Buffaloes were able to pull out the upset as he was seemingly unstoppable and just dominated Mike Anderson's defense for the entire game.
He finished with 36 points, including three-for-three on shots behind the arc and he added eight rebounds in a career day for the Colorado super sophomore.
Colorado controlled the entire game as they went on two separate 15-2 runs to make sure that the Tigers were never at arm's length in this contest.
The Buffaloes, under first-year head coach Tad Boyle, took a 12-point lead into halftime and never looked back against the No. 3 ranked Missouri Tigers.
Sophomore guard Mike Dixon lead the way for the Tigers as he scored 17 points, while junior forward Laurence Bowers added 15 points and a career-high eight blocks in the losing effort.
In the end, it was a rough start to a pivotal conference part of the season that could essentially make or break this current version of Mike Anderson's Missouri team.
How many conference wins will the Tigers get this year?
The Tigers need to put this loss behind them as they look ahead to the Nebraska Cornhuskers this week at Mizzou Arena.
They will need to start playing better overall team defense and players like junior guard Kim English (who only had two-of-10 shooting for seven points against CU) need to step up their game in order for the Tigers to secure their third-straight NCAA tournament berth in March.
There is still much work to be done with this team, but the "real" part of the season has now begun and it continues against Nebraska on Wednesday night.