CB Pierre Desir, Lindenwood
A big, physical cornerback, Desir is a Day 2 talent that has slipped. There is a low chance of him getting to the Colts' pick at No. 166, but he's the kind of talent that would be worth trading up for. Desir has the potential to develop into an excellent, physical press cornerback.
S Ed Reynolds, Stanford
Like Desir, Reynolds may not last until the late fifth round, but he's the kind of safety that the Colts need, versatile and physical. He would give Delano Howell good competition at the safety position.
CB Jaylen Watkins, Florida
Give a guy like Watkins to the defense to use, there are plenty of ways. Watkins played corner and safety at Florida, and he has the kind of versatility the Colts could use in an injury-prone defensive backfield. Give the Colts that versatility and let Chuck Pagano mold him into the best tool that he can be.
OLB Carl Bradford, Arizona State
The Colts spent time with Bradford at his pro day at Arizona State, and it's surprising he's lasted this long. He's the best outside linebacker talent left on the board, and the Colts need depth at the linebacker position. Bradford likely won't be an elite pass-rusher in the NFL, but he can play either down or standing up, inside or outside. He can blitz or drop back. If you're sensing a pattern with these prospects, there's a reason for that.
ILB Yawin Smallwood, Connecticut
A nickel linebacker in the NFL, Smallwood would add to the depth at inside linebacker and give the Colts more pass-rushing options from the inside linebacker spot. He'd contribute right away on special teams and allow the Colts to move on from some of the unreliable depth in the rotation.
S Craig Loston, LSU
A good in-the-box defender at LSU, Loston projects as a strong safety in the NFL. He was a strong locker-room presence at LSU, and he would fit in with the Colts' locker room very well. For a strong safety, his route recognition and football I.Q. are very high. He'd also be an exceptional special teams player right away.