The 2012 U.S. Open proved to be historic on Wednesday, as the singles career of three-time U.S. Open champion Kim Clijsters came to an end after her second-round defeat.
Aside from Clijsters going down in consecutive-set tiebreakers, the rest of the heavyweights on the men's and women's side, including Maria Sharapova, moved through.
Let's take a closer look at the notable Day 3 scores and highlight the top storylines.
Here are some notable scores from Wednesday's action at Flushing Meadows:
Victoria Azarenka (1) defeated Kirsten Flipkens 6-2, 6-2
Andy Murray (3) defeated Ivan Dodig 6-2, 6-1, 6-3
David Ferrer (4) defeated Kevin Anderson 6-4, 6-2, 7-6 (7-3)
Maria Sharapova (3) defeated Lourdes Dominguez Lino 6-0, 6-1
Juan Martin del Potro (7) defeated Florent Serra 6-4, 7-6 (7-4), 6-4
John Isner (9) defeated Xavier Malisse 6-3, 7-6 (7-5), 5-7, 7-6 (11-9)
Samantha Stosur (7) defeated Edina Gallovits 6-3, 6-0
Petra Kvitova (5) defeated Alize Cornet 6-4, 6-3
Li Na (9) defeated Casey Dellacqua 6-4, 6-4
Laura Robson defeated Kim Clijsters (23) 7-6 (7-4), 7-6 (7-5)
Janko Tipsarevic (8) defeated Giullaume Rufin 4-6, 3-6, 6-2, 6-3, 6-2
Click here to see a full list of scores from Day 3 at the 2012 U.S. Open.
John Isner Prefers the Drama
After watching John Isner go back and forth with Tomas Berdych in the Winston-Salem Open final last Saturday, it seemed like he played his best tennis when he was under the most pressure.
Well, there is no more pressure-packed situation in the sport than during a tiebreaker. Isner found himself in not one, but two against Xavier Malisse on Day 3 at Flushing Meadows.
The 6'9" American won in four sets, but two of his winning sets needed tiebreakers. Isner's 7-5 win to decided the second set was clutch. But then he followed that up with a 11-9 win in the fourth set tiebreaker.
It is becoming more obvious as the summer wears on: Isner prefers the drama.
A Sad Farewell to Kim Clijsters
The 29-year-old Clijsters announced long before this year's U.S. Open that Flushing Meadows would be her final tournament, but still her retirement from tennis seems shocking.
The Belgian fell in straight sets to British player Laura Robson in the second round on Wednesday. Both sets needed tiebreakers, though, proving Clijsters wouldn't go away easy.
Day 3 marked the last day fans would see Clijsters in singles action. The four-time Grand Slam champion was given a heartwarming ovation by those in attendance and will still have one last chance to be a champion again in doubles play.
Andy Murray Poised to Win His Bracket
It was less than a month ago that Andy Murray defeated the world's top two tennis players in a period of two days at the 2012 London Olympic Games.
Murray's destruction of Roger Federer in the gold-medal match on Wimbledon's Centre Court has no doubt given him the confidence he needs to win his first career Grand Slam.
Murray eliminated Ivan Dodig in the second round on Wednesday like it was nothing, topping him 6-2, 6-1, 6-3 to advance to the third round for the sixth consecutive time in Queens.
After winning his first two matches at this year's tournament in straight sets each, Murray looks poised to win his bracket with ease, ultimately securing himself a rematch with Federer in the semifinals.
Follow Bleacher Report Featured Columnist Patrick Clarke on Twitter for more reaction and analysis on the 2012 U.S. Open.