Clive Brunskill/Getty Images
How they got here
Serena had two easy straight-set wins in her first two rounds, beating down on Barbora Strycova and Melinda Czink. Her last match, against 25th seed and former Wimbledon semifinalist Jie Zheng, was quite a bit tougher, as she came from a set down to win 9-7 in the fifth.
Shvedova has, surprisingly, had a much easier route to the fourth round. Through matches with Chanelle Scheepers, Kiki Bertens and even 10th seed and French Open finalist Sara Errani, the Kazakh has yet to drop a set.
There's rarely a substitute for experience in Grand Slams, and that advantage obviously goes to Serena. Before this year, Shvedova had never been out of the second round of Wimbledon, while Williams is the four-time champion.
However, Serena had both a three-set thriller with Jie Zheng and split two sets in doubles on Saturday.
Also, Shvedova has played well in both of her quarterfinal appearances at the French Open.
I won't go so far as to predict the upset, but Shvedova may be able to nick a set off of Serena.