On Tuesday at the French Open, Serena Williams lost in the opening round of a major for the first time in her career. The younger Williams sister showed signs of aging, as she fell short of a third-set comeback and fell to Virgine Razzano of France 4-6, 7-6(5), 6-3.
When a player of Williams' stature gets knocked out in the first round at Roland Garros, it turns the entire tournament on its head.
Who stands to gain from this early upset? Whose draw just got that much more interesting? And if Serena Williams was beaten in the first round, who else is at risk?
Eighth-seeded Marion Bartoli lost in the second round on the women's side, and men's 10th seed John Isner was also ousted. The third round is under way in Paris, and we will soon find out who else will fall.
Until then, here are the eight men's and women's players with the best chances to make it through their draws and take a shot at a French Open championship.