Rooney will miss all three of England's group games at next summer's European Championship, leaving manager Fabio Capello with some interesting choices on who to replace him with.
England didn't look particularly good in their recent qualifying matches, and one of the few bright spots since the 2010 World Cup debacle has been the play of Rooney.
Rooney has been in top form for club and country this season, and is the only forward who puts fear into the defenses of the top European teams.
Without their most dangerous scorer, England will have to pick up the slack as a unit.
Capello has a number of choices to play at forward in Rooney's place, and choosing the right one will be crucial to the team's chances at doing well at the Euro's, and surviving the group stage.
Darren Bent, Andy Carroll, Danny Welbeck and Jermain Defoe are the best choices to replace Rooney at center forward.
Ashley Young led the team in qualifying with three goals, but he is most effective on the wing, and it's unlikely he would be moved into a more central role.
Would Steven Gerrard move up from the midfield? Probably not, he is best served in the central midfield, setting up the forwards with brilliant scoring opportunities.
In terms of experience, Defoe and Bent have the edge, and that's why they should be the favorites to play Rooney's role in the Euro group stages.
Bent has a great shot and possesses good pace, and has a wealth of experience playing at the international level. Defoe has a powerful shot and makes solid runs, and also has pretty good pace.
The interesting choice is Welbeck. The young Manchester United player has been quite impressive this season, and has made several starts for Sir Alex Ferguson's side.
Welbeck plays with great energy and attacks the net. This energy would probably be best used as a substitute when Capello needs to bring on fresh legs to ignite the attack.
Carroll is an option, but other than heading, he doesn't give Capello anything better than what Bent and Defoe can bring to the team.
Wayne Rooney's three-match ban will make it difficult for England to advance past the group stages of Euro 2012. They have a good amount of talent to replace him, but none of those players bring the scoring threat Rooney does.
Rooney has been on fire this season for club and country, and his absence in the scoring attack will be hugely missed.
Capello must find the best replacement for Rooney quickly, because the longer it takes him to find the right fit, the harder of a time England will have in advancing to the Euro Finals.
Nicholas Goss is a Featured Columnist at Bleacher Report, follow him on Twitter for the latest sports news and updates. Follow @NicholasGoss35