ARLINGTON, TEXAS - DECEMBER 29: A Clemson Tigers player holds up his helmet before the game against the Notre Dame Fighting Irish during the College Football Playoff Semifinal Goodyear Cotton Bowl Classic at AT&T Stadium on December 29, 2018 in Arlington, Texas. (Photo by Tom Pennington/Getty Images)Tom Pennington/Getty Images

2020 College Football Odds: Clemson, Ohio State, Alabama Favorites to Win CFP

Megan ArmstrongJun 8, 2020

The LSU Tigers defeated the Clemson Tigers 42-25 in the 2020 College Football Playoff National Championship Game, but Clemson is favored to come out on top in the 2021 title game, according to Caesars Palace's latest odds.

Clemson (+250, bet $100 to win $250) is favored ahead of Ohio State (+300), Alabama (+500) and Georgia (+700). Reigning undefeated champion LSU, who tied an NFL record with 14 players getting drafted in April, has +1800 odds.

While LSU saw Heisman Trophy-winning quarterback Joe Burrow go No. 1 overall to the Cincinnati Bengals, Clemson is bringing back Trevor Lawrence. However, Clemson was handed a big blow when wide receiver Justyn Ross was announced last week as out for the season with a congenital spinal issue.

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Clemson's loss to LSU marked its first since dropping the 2018 title game 24-6 to Alabama.

The 2020 college football season is scheduled to begin Aug. 29, but the possibility remains for a delayed or shortened season because of the ongoing COVID-19 pandemic.