Because of their involvement in the 2019 FIFA Club World Cup in Qatar, Liverpool's December schedule is even more packed than usual for an English side:
As a result, Klopp was forced to play a weakened side against Everton at Anfield in midweek, when Liverpool maintained their eight-point lead at the top of the Premier League table with a 5-2 win.
Mohamed Salah, Jordan Henderson and Roberto Firmino all started on the bench, but a number of squad players stepped in impressively, with Xherdan Shaqiri scoring in his first start of the season and Divock Origi netting a double.
Klopp hinted he will likely have to rotate again for Saturday's trip to Bournemouth but added Liverpool fortunately have no fresh injury worries:
The German manager also backed Sadio Mane to work his way even further up the Ballon d'Or rankings after he finished fourth in the voting for the 2019 award.
Lionel Messi won the prestigious gong for a record sixth time at a ceremony in Paris on Monday. But Liverpool, as European champions, were the most well-represented club in the top 10, with Virgil van Dijk runner-up, Mane fourth, Mohamed Salah fifth and goalkeeper Alisson seventh:
In a video message recorded in response to the result, Mane said he hoped to attend the gala next year to "maybe lift the Ballon d'Or."
Klopp said he is confident Mane can improve even further:
Liverpool have had no problem brushing Bournemouth aside in recent seasons. They have won their last four fixtures against the Cherries by a combined score of 14-0, and Eddie Howe's side are also on a four-game losing run.
The hosts may sniff an opportunity to get a shock result on Saturday, though, given Liverpool's schedule.
Unfortunately for Klopp, he cannot afford to field a weakened side on Tuesday in the UEFA Champions League because Liverpool need to avoid defeat at Red Bull Salzburg or else risk crashing out at the group stage.