The inaugural CONCACAF Nations League group stage begins on Thursday, with the tournament to provide qualification for the 2021 Gold Cup.
Following a similar format to UEFA's Nations League, the four League A group winners will advance to the finals of the competition in June 2020.
Bermuda take on Panama in the opening action for League A (Group B) on Thursday, with the League B and League C fixtures also beginning this week.
Canada and Cuba kick off their group on Sunday in League A (Group A). The United States are set to feature as a top-four seed but do not play until October 11 when they face the Cubans in their opener.
September's Nations League Fixtures and Score Predictions
Thursday, Sept. 5
U.S. Virgin Islands vs. Cayman Islands, 3 p.m ET, 8 p.m. BST, 1-1
Dominica vs. Suriname, 3 p.m ET, 8 p.m. BST, 2-1
Bermuda vs. Panama, 6 p.m ET, 11 p.m. BST, 1-4
Grenada vs. Saint Kitts and Nevis, 6 p.m ET, 11 p.m. BST, 3-0
Barbados vs. Saint Martin, 6 p.m ET, 11 p.m. BST, 3-0
French Guiana vs. Belize, 8 p.m. ET, 1 a.m. BST (Friday), 1-1
Nicaragua vs. Saint Vincent and the Grenadines, 8 p.m. ET, 1 a.m. BST (Friday), 2-1
Guatemala vs. Anguilla, 10 p.m. ET, 3 a.m. BST (Friday), 0-0
Friday, Sept. 6
Bonaire vs. British Virgin Islands, 3 p.m ET, 8 p.m. BST, 1-1
Martinique vs. Trinidad and Tobago, 6 p.m ET, 11 p.m. BST, 1-3
Aruba vs. Guyana, 7 p.m. ET, midnight BST (Saturday), 2-2
Jamaica vs. Antigua and Barbuda, 8 p.m. ET, 1 a.m. BST (Saturday), 3-0
Saturday, Sept. 7
Montserrat vs. Dominican Republic, 3 p.m ET, 8 p.m. BST, 1-0
Guadeloupe vs. Sint Maarten, 5 p.m. ET, 10 p.m. BST, 0-0
Curacao vs. Haiti, 6 p.m ET, 11 p.m. BST, 2-1
Canada vs. Cuba, 8 p.m. ET, 1 a.m. BST (Sunday), 3-1
El Salvador vs. St. Lucia, 10 p.m. ET, 3 a.m. BST (Sunday), 2-0
Sunday, Sept. 8
Saint Vincent and the Grenadines vs. Dominica, 3 p.m ET, 8 p.m. BST, 1-1
Saint Martin vs. U.S. Virgin Islands, 3 p.m ET, 8 p.m. BST, 1-0
Belize vs. Grenada, 6 p.m ET, 11 p.m. BST, 3-1
Suriname vs. Nicaragua, 6 p.m ET, 11 p.m. BST, 1-2
Saint Kitts and Nevis vs. French Guiana, 7 p.m. ET, midnight BST (Monday), 1-1
Cayman Islands vs. Barbados, 7:30 p.m. ET, 12:30 a.m. BST (Monday), 1-2
Panama vs. Bermuda, 9 p.m. ET, 2 a.m. BST (Monday), 3-1
Monday, Sept. 9
Antigua and Barbuda vs. Aruba, 3 p.m ET, 8 p.m. BST, 2-2
Bahamas vs. Bonaire, 6 p.m. ET, 11 p.m. BST, 3-1
Guyana vs. Jamaica, 7 p.m. ET, midnight a.m. BST (Tuesday), 1-2
Trinidad and Tobago vs. Martinique, 9 p.m. ET, 2 a.m. BST (Tuesday), 2-1
Tuesday, Sept. 10
Turks and Caicos Islands vs. Guadeloupe, 3 p.m. ET, 8 p.m. BST, 2-0
Montserrat vs. St. Lucia, 4 p.m. ET, 9 p.m. BST, 2-2
Haiti vs. Curacao 6 p.m ET, 11 p.m. BST, 1-3
Dominican Republic vs. El Salvador, 6 p.m ET, 11 p.m. BST, 0-1
Cuba vs. Canada, 7:15 p.m. ET, 12:15 a.m. BST (Wednesday), 1-2
Puerto Rico vs. Guatemala, 9 p.m. ET, 2 a.m. BST (Wednesday), 1-1
Further Nations League fixtures to be confirmed by CONCACAF via the tournament's official website. See the Nation League website for full group information.
CONCACAF Announce 2021 Gold Cup Path
With the top seeds missing from the opening day of the Nations League, the spotlight falls on some of the lesser lights.
Canada and Cuba clash in League A (Group A) on Sunday, with the USA completing the three-team collective.
CONCACAF upped the competition stakes by announcing on Wednesday Gold Cup qualification will be linked to the final Nations League standings.
The governing body's official Twitter account explained the path to qualification:
Bermuda could be the surprise package in League A (Group B), and they begin their group campaign against Panama.
Mexico are the primary seed in Group B, but the Panamanians qualified for the 2018 FIFA World Cup in Russia and were quarter-finalists at the 2019 Gold Cup, proving their mettle.
El Tri do not begin their tournament until October 15 when they host Panama.