The north London derby between Arsenal and Tottenham Hotspur will take centre stage during Week 4 of the 2019-20 Premier League season.
The two rivals will clash on Sunday in what will be the final league contest before the international break.
Elsewhere, Manchester United visit Southampton, Manchester City host Brighton & Hove Albion, Chelsea face Sheffield United, and Liverpool travel to Burnley.
Here is a look at the schedule for Week 4, complete with score predictions:
Saturday, August 31
12:30 p.m. BST: Southampton vs. Manchester United (1-1)
3 p.m. BST: West Ham vs. Norwich (2-1)
3 p.m. BST: Leicester vs. Bournemouth (2-0)
3 p.m. BST: Manchester City vs. Brighton (4-1)
3 p.m. BST: Newcastle vs. Watford (0-0)
3 p.m. BST: Chelsea vs. Sheffield United (1-0)
3 p.m. BST: Crystal Palace vs. Aston Villa (1-1)
5:30 p.m. BST: Burnley vs. Liverpool (0-2)
Sunday, September 1
2 p.m. BST: Everton vs. Wolverhampton (2-2)
4:30 p.m. BST: Arsenal vs. Tottenham (1-1)
Spurs will travel to the Emirates Stadium with plenty of question marks surrounding the team following the 1-0 upset loss against Newcastle United.
The Magpies came into the contest without any points but held their own relatively easily against Spurs. The video assistant referee could have handed the hosts a penalty for contact between Harry Kane and Jamaal Lascelles, but all in all, Tottenham created far too few dangerous looks.
Manager Mauricio Pochettino has admitted all is not well with the squad, per sports writer Alasdair Gold:
Alasdair Gold @AlasdairGold
Here's every word Pochettino has just said, on Eriksen, whether he's going to leave and a very interesting answer about the squad. Says it's the most unsettled squad he's ever had at Spurs and there are lot of problems he can't fix until the windows close. https://t.co/ohoAdI47Of
The Gunners are also coming off a loss, with individual mistakes proving costly against Champions League titleholders Liverpool. Unai Emery's troops look far more settled, however, and will feel good about their chances in the derby.
Manchester United also suffered a surprise defeat in Week 3, losing at home to Crystal Palace, and will now travel south for a date with Southampton.
Things have not gone well since manager Ole Gunnar Solskjaer got the job on a permanent basis:
Saints won their first match of the season in Week 3 against Brighton and appear ready to turn the corner.
Liverpool will put their perfect record on the line away to Burnley, who battled to draw against Wolves after conceding a late penalty.
Reds boss Jurgen Klopp loved what he saw from his players in the win over the Gunners:
City cruised to a win away to Bournemouth and will be strong favourites again when they host Brighton at the Etihad Stadium.