Per AS, the Atletico boss has been critical of the atmosphere at the Santiago Bernabeu and also suggested Modric and Courtois' individual prize successes were helped by the fact that they play for Los Blancos.
Speaking to Sportske Novosti (h/t AS), Modric, who recently won the Ballon d'Or, responded to the comments from Simeone:
"I can understand Simeone defending one of his own players, [Antoine] Griezmann, and thinking he was the best, but it's to his detriment that he feels the constant need to belittle Real Madrid and our players. He takes advantage of every opportunity to imply there is something else behind Real Madrid's triumphs which is totally false."
Courtois, who played under Simeone at Atletico, said his former manager makes comments like this in order to appease his club's supporters.
"Simeone criticises Madrid so as to be popular with his fans," he said, per AS. "He always does it, attacks Madrid for being the best in the world."
Modric has been a central figure in Los Blancos' recent dominance of European football, helping the team win the UEFA Champions League three times in a row and in four of the past five seasons. His displays in the competition and with Croatia at the FIFA World Cup were key to his recent crowning as the best player on the planet.
Courtois joined Real in the summer from Chelsea, but as Bet365 relayed, things haven't gone well for the Belgium international or his new team since:
Thibaut Courtois joins Real Madrid: - Real Madrid's worst start to La Liga season ever - Real Madrid's second biggest El Clasico loss since 1994 - Real Madrid's first home loss in the group stages since 2009 - Real Madrid's biggest European home defeat ever Chelsea fans: #CFC https://t.co/9KMjgewtaf
It was during a loan spell with Atletico when Courtois forged a reputation as one of the best goalkeepers in the world. He helped Simeone's team win a shock La Liga title in the 2013-14 season and helped the team to the Champions League final in the same campaign, where they lost to Madrid.
Courtois was part of the trademark defensive stability Simeone's teams enjoy. His record as manager of Atletico has been remarkable from that standpoint:
Atletico kept up the pressure on La Liga leaders Barcelona on Saturday, as they beat Real Valladolid 3-2. The Blaugrana, on the same points as Atletico, are in action on Sunday, when they travel to Levante.
While the Madrid derby is always a fiery affair, the comments from Simeone, Modric and Courtois should make the next one especially spicy. The two sides are scheduled to meet on February 10 at the Wanda Metropolitano.