The Colorado Rockies (79-64) will look to continue their recent dominance of the Arizona Diamondbacks (76-68) on Tuesday when they host them again as small home underdogs at sportsbooks in the second game of a key four-game divisional series.
The Rockies own a 1.5-game lead over the Los Angeles Dodgers in the National League West, with the Diamondbacks three games back after losing 13-2 on Monday.
MLB betting pick, via OddsShark computer: 4.5-4.3, Rockies (MLB picks on every game)
Why the Diamondbacks can pay on the MLB lines
Arizona has dropped five of the past six meetings with Colorado, according to the OddsShark MLB Database, but fortunately for the D-backs, ace Zack Greinke (13-9, 3.08 ERA) will toe the rubber in one of the team's most important games of the season.
While the 34-year-old is winless in his last two starts, the Diamondbacks would not want any other pitcher going to the mound in this spot.
Greinke is 2-0 with a 2.33 ERA in three outings versus the Rockies this season, and one of those wins took place at Coors Field.
Why the Rockies can pay on the MLB lines
Colorado has more momentum than any team in the division right now and plays the next 12 games against NL West foes, including six more versus Arizona.
The Rockies will counter Greinke with Antonio Senzatela (4-5, 4.92 ERA), and he has earned three of his wins at Coors this year.
Last time out, the 23-year-old allowed three runs and nine hits in five innings with two walks and six strikeouts against the San Francisco Giants on Wednesday, and Colorado was able to pull off a 5-3 victory.
If Senzatela can avoid pitching worse than that here, the Rockies will have a solid chance to win.
Smart betting pick
Even though Senzatela has picked up three of his four wins at home, his ERA is 5.04 and opposing hitters are hitting .328 against him there. That is not good obviously, and he is also 0-2 with a 6.75 ERA in two games versus the D-backs this season.
This is a must-win matchup for Arizona, so look for the team to back up its status as a road favorite by coming through with a big victory to end its three-game losing streak.
MLB betting trends
The total has gone over in each of Arizona's last five games.
The total has gone over in four of Arizona's last six games against Colorado.
Arizona is 15-8 in its last 23 games when playing Colorado.
All MLB odds and betting trends according to Bleacher Report's official odds partner, OddsShark. Check out OddsShark on Twitter and Instagram or head to YouTube for more betting picks and analysis on this week's top games. You can also download the free odds tracker app.