The Europa League group stage wrapped up on Thursday, and 24 teams went through to join the eight third-placed Champions League teams set for the last-32 draw on Monday.
Seedings will be crucial, as each qualified side will be looking for the easiest draw possible, with the aim of going deep in European competition this season.
Unlike previous editions, this year's winners will qualify for next term's Champions League, giving Monday's draw even greater importance.
Here are all the relevant details ahead of the draw for the Europa League's first knockout stage, including a full list of participants and seedings.
Date: Monday, Dec. 15
Time: noon GMT, 7 a.m. ET
TV Info: Sky Sports News HQ (UK only)
|Europa League Draw: List of Teams|
|Europa League Group Winners||Europa League Group Runners-up|
|Dinamo Moscow||PSV Eindhoven|
|Inter Milan||Dnipro Dnipropetrovsk|
|Napoli||BSC Young Boys|
|Dynamo Kiev||Aalborg BK|
|Top Champions League Transfers||Bottom Champions League Transfers|
|Zenit Saint Petersburg||Roma|
No team can be drawn against a club from their group or from the same association, per UEFA.
For those clubs who qualified top of their group, an easier ride through the first knockout round is supposed to be the reward.
However, there is some serious quality in the unseeded group this season, each of whom could spell danger if drawn.
The likes of Tottenham, Villarreal and reigning champions Sevilla all came second in their groups and thus stand to face one of the seeded sides.
The teams who came third in their Champions League groups could also pose a serious threat in the last 32, with Roma, Anderlecht, Ajax and Liverpool all unseeded.
Equally, the lack of seeding could prove to be a major issue for the likes of Liverpool and Spurs, the Daily Mail pointing out that Brendan Rodgers' Reds have paid more than once for their poor showing on their return to the Champions League this term:
Spurs could pay dearly for their inability to claim a point against Besiktas on Thursday, the 1-0 loss resulting in the Turkish club leapfrogging the north London side into top spot in the group.
As a result, Mauricio Pochettino could be faced with a significant challenge, per 101 Great Goals:
Indeed, Tottenham could end up facing to their old boss Andre Villas-Boas if they are drawn against Zenit Saint Petersburg, while Liverpool could be on for a showdown with Rafa Benitez's Napoli.
There is plenty of quality left in the Europa League and the potential for some cracking matchups at the last-32 stage.
The only two teams not to lose a single match during the Europa League group stage were FC Red Bull Salzburg—who dropped just two points, drawing their opener against Celtic—and all-conquering Dinamo Moscow, who won every match.
Form is an important thing in competition football, and both these sides will be tricky opponents as the tournament advances.
However, neither is anything close to a favourite for winning the competition, with Italian trio Roma, Napoli and Inter being fancied by many.
Indeed, Roma are currently second in Serie A, just one point behind Juventus, and they will be desperate for European success after being dumped out of the Champions League by Manchester City in their final group game on Wednesday.
After a hard-fought group stage, things get tougher in the knockout rounds, and with so many teams still left in the competition, the chances of a simple draw are next to nothing.
All will be revealed on Monday, and there should well be some mouth-watering ties to look forward to when the competition gets back up and running in February, with each team looking toward the Warsaw final.