49ers vs. Eagles: NFC Championship Odds and Over-Under Predictions

The 2022 NFL regular season established the Philadelphia Eagles and San Francisco 49ers as the top two teams in the NFC.

Come Sunday afternoon, one will officially capture conference supremacy, not to mention scoring a ticket to Super Bowl LVII.

For now, though, oddsmakers don't see much difference between the two teams. The Eagles are slightly favored, but that makes sense when they have home-field advantage and aren't the team starting a rookie quarterback who opened the campaign third on the depth chart.

Still, that rookie quarterback, Brock Purdy (last year's Mr. Irrelevant), is undefeated since taking over for an injured Jimmy Garoppolo. In fact, San Francisco last dropped a game in Week 7. Including the playoffs, the Niners have won 12 consecutive contests, only four of which were decided by single digits.

In other words, football fanatics might be in line for an instant classic come Sunday. To help set the stage, we'll examine the latest odds from DraftKings Sportsbook and make a pair of wager-based predictions.

NFC Championship Game Schedule, Odds

Bob Kupbens/Icon Sportswire via Getty Images

SANTA CLARA, CA - JANUARY 22: San Francisco 49ers running back Christian McCaffrey (23) warms up before the NFL NFC Divisional Playoff game between the Dallas Cowboys and San Francisco 49ers at Levis Stadium in Santa Clara, CA. (Photo by Bob Kupbens/Icon Sportswire via Getty Images)

What: No. 2 49ers at No. 1 Eagles

When: Sunday, Jan. 29 at 3 p.m. ET

Where: Lincoln Financial Field, Philadelphia.

Point spread: Eagles -2.5

Moneyline: Eagles -145; 49ers +125

Over/under: 46

Prediction: The Under Hits

Tim Nwachukwu/Getty Images

PHILADELPHIA, PENNSYLVANIA - JANUARY 01: Darius Slay #2 of the Philadelphia Eagles looks on against the New Orleans Saints during the second quarter at Lincoln Financial Field on January 01, 2023 in Philadelphia, Pennsylvania. (Photo by Tim Nwachukwu/Getty Images)

On paper, this matchup looks exhausting for both offenses.

The 49ers and Eagles ranked first and second, respectively, in yards allowed per game this season. San Francisco ceded 300.6, while Philly yielded 301.5. The Washington Commanders (304.6) were the league's only other club to allow fewer than 311 per tilt.

Scoring defense saw a slightly larger gap between the teams, but both still ranked among the league's elite. The 49ers allowed a league-best 16.3 points per game, and the Eagles tied for the seventh-fewest at 20.2.

The 49ers tied for second with 30 takeaways; the Eagles tied for fourth with 27. The Eagles flirted with history while pacing everyone with a jaw-dropping 70 sacks; the 49ers tied for 10th with 44, 18.5 of which came from NFL sack leader (and Defensive Player of the Year candidate) Nick Bosa.

As we said, these offenses have their work cut out for them.

The offensive firepower is theoretically present for these teams to push past a 46-point total, but we wouldn't bet against these defenses.

Prediction: The 49ers Cover

Michael Owens/Getty Images

SANTA CLARA, CALIFORNIA - JANUARY 22: Brock Purdy #13 of the San Francisco 49ers passes the ball during an NFL divisional round playoff football game between the San Francisco 49ers and the Dallas Cowboys at Levi's Stadium on January 22, 2023 in Santa Clara, California. (Photo by Michael Owens/Getty Images)

Basic logic likes the Eagles here. They lost once all season with a healthy Jalen Hurts—he missed the Week 16 and 17 losses with a shoulder sprain—and seemed to regain superteam status in their 38-7 dismantling of the New York Giants in the divisional round.

"To have him out there, I know this is high praise, it's like having Michael Jordan out there," Eagles head coach Nick Sirianni told reporters. "He's your leader. He's your guy. That's the biggest respect I can pay to him."

Philadelphia is awesome—no, like all-caps AWESOME. There's a reason the Eagles have the best Super Bowl odds of anyone (+240).

And yet, how can we act like San Francisco isn't sending out serious team-of-destiny vibes during this run with Purdy at the helm? The first-year signal-caller has done a masterful job of staying within himself and letting the 49ers' talent (and Kyle Shanahan's play-calling) shine.

"In San Francisco, they don't rely on the quarterback's production as much as most teams," one coach told The Athletic's Bruce Feldman. "It also helps that they have the best left tackle, one of the best tight ends, one of the best running backs, one of the best wide receivers and a really good defense—they are loaded around him."

If Purdy keeps taking advantage of all the playmakers around him, San Francisco has the personnel to not only cover the spread but also win this game outright.

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