J.C. Jackson's status for the Los Angeles Chargers' season opener against the Las Vegas Raiders on Sept. 11 at SoFi Stadium is up in the air.
The veteran defensive back had ankle surgery Tuesday, and his return timetable is between two to four weeks, according to ESPN's Adam Schefter. L.A.'s season opener is a little more than two weeks away.
The news comes after Jackson did not practice with the Chargers on Monday because of an undisclosed injury.
NFL Network's Ian Rapoport added that Jackson underwent a scope procedure and it's considered "pretty minor."
Jackson was one of L.A.'s marquee offseason acquisitions. The two sides agreed to a five-year, $82.5 million contract in March, putting him among the league's highest-paid defensive backs at $16.5 million annually, per Spotrac.
The 26-year-old spent the first four seasons of his career with the New England Patriots, who signed him as an undrafted free agent in 2018. However, he didn't have a breakout campaign until 2020, when he posted nine interceptions, 14 pass breakups, three fumble recoveries and 40 tackles in 16 games, including 11 starts.
Jackson is coming off the best season of his career in 2021, having posted eight interceptions, a league-leading 23 pass breakups, one forced fumble and 58 tackles in 17 games en route to his first Pro Bowl selection.
That led to the Florida native being ranked as the No. 1 player on NFL.com's top cornerbacks list entering 2022, putting him above Jalen Ramsey, Xavien Howard, A.J. Terrell and Patrick Surtain II.
"The former Patriot is a physical corner who plays the ball tremendously well [league-high 24 takeaways since 2019]," NFL.com's David Carr wrote. "He's the type of player quarterbacks are terrified to throw toward because even if a receiver has a step on Jackson, he's still not open."
Jackson is slated to be one of the team's starting outside cornerbacks in 2022, likely opposite Asante Samuel Jr. If he's unable to suit up for Week 1, Michael Davis and Deane Leonard could see more playing time.