During an appearance on the Huddle & Flow podcast with NFL Network's Steve Wyche, Jim Trotter and Thomas Warren, Ramsey said (around the 18-minute mark) of his close friend: "I highly doubt he'll ever suit up in a Texans uniform again. He's very serious."
ESPN's Adam Schefter (h/t Sarah Barshop) reported in January that Watson formally asked the Texans for a trade due, in part, to his frustration over not being included in the decision-making process before Houston hired former New England Patriots executive Nick Caserio as its new general manager.
Last month, ESPN's Dan Graziano reported that Watson met with new Texans head coach David Culley and told him during that meeting he has "no intention" of ever playing for the Texans again.
Watson and Ramsey are longtime rivals on the field, as they both played at ACC schools in Clemson and Florida State, respectively, before clashing in the AFC South with Watson playing for the Texans and Ramsey playing for the Jacksonville Jaguars before getting traded to the Rams.
They are friends off the field, however, meaning Ramsey may have some legitimate insight into Watson's plans for the future.
The 25-year-old Watson is coming off a career year statistically in 2020, as he completed 70.2 percent of his passes for an NFL-leading 4,823 yards, as well as 33 touchdowns and seven interceptions. He also rushed for 444 yards and three scores.
Despite Watson's best efforts, the Texans went just 4-12, and there may be no immediate end in sight to their struggles regardless of whether Watson stays or goes.
The Texans released franchise sack leader and three-time NFL Defensive Player of the Year J.J. Watt, who signed with the Arizona Cardinals this week. They also sent another key player to the Cardinals last March, trading wide receiver DeAndre Hopkins and a 2020 fourth-round pick to Arizona for a 2020 second-rounder, a 2021 fourth-rounder and running back David Johnson in a widely panned move.
To top it off, the Texans do not pick until the third round of the 2021 draft after trading their first- and second-round picks to the Miami Dolphins in a deal for offensive tackle Laremy Tunsil, meaning making improvements this offseason will be difficult.
Watson has plenty of reasons in wanting to leave, although that decision may not entirely be in his hands.
Since Watson is signed through 2025, the Texans are under no obligation to trade Watson, meaning he may have to force their hand by holding out in order to make a trade happen.
Should the Texans decide to part ways with him, several teams are believed to be interested, including the New York Jets, Miami Dolphins, Carolina Panthers and Chicago Bears.
Losing Watson would be devastating to the Texans since he is a legitimate franchise quarterback, but a Watson trade would help them restock a draft-pick cupboard that is currently barren.