NFL Week 11 Picks: Latest Odds, Spreads and Updated Midweek Predictions

Midweek NFL odds out of Las Vegas continue to be the way to go.

Last week, bettors could have grabbed the Kansas City Chiefs, seven-point dogs to the Denver Broncos despite their first contest ending in a seven-point differential and Peyton Manning's continued downward spiral.

Now would be the time to find similar value before lines move too much. Given the never-ending nature of the NFL, those who take shots now usually come out on top, so here's a look at the full Week 11 slate.

NFL Week 11 Odds 

Game	Spread	O/U	Predicted Winner
Tennessee at Jacksonville	JAC -2.5	43	JAC 27-14
Indianapolis at Atlanta	ATL -7	47.5	IND 23-20
St. Louis at Baltimore	BAL -1	41.5	STL 17-10
Washington at Carolina	CAR -8.5	45	CAR 24-14
Denver at Chicago	E	41	DEN 28-20
Oakland at Detroit	OAK -1	48	OAK 30-24
N.Y. Jets at Houston	NL	--	NYG 26-23
Dallas at Miami	E	47.5	DAL 20-16
Tampa Bay at Philadelphia	PHI -7	45.5	PHIL 28-23
Kansas City at San Diego	KC -2.5	44	KC 23-17
Green Bay at Minnesota	E	44.5	MIN 24-23
San Francisco at Seattle	SEA -13.5	40	SEA 27-20
Cincinnati at Arizona	ARI -4	48	CIN 20-17
Buffalo at New England	NE -7.5	48	NE 33-24

Odds courtesy of Odds Shark.    

Mid-Week Lines to Bet

Indianapolis at Atlanta (-7)

It's easy to jump all over the Atlanta Falcons here and call it day, in large part because Andrew Luck won't be available.

That might be a huge mistake, though, which is perhaps why this line isn't bigger in the first place. Look at the Falcons, who have lost three of their last four and their grip on the NFC South as they choke on an almost weekly basis.

In fact, Atlanta needed overtime to beat Washington before losing to New Orleans, just winning 10-7 against the 2-7 Tennessee and then dropping games to Tampa Bay (4-5) and San Francisco (3-6).

Meanwhile, it's not like the Colts have looked terrible with veteran Matt Hasselbeck under center, as he's 2-0 this year with three touchdowns to no interceptions.

With Matt Ryan throwing six touchdowns to five interceptions in the aforementioned time span, this one will be much closer than most would figure. In fact, look for an outright upset as the veteran Hasselbeck takes care of the football and capitalizes on mistakes, which seems to be the focal point surrounding these borderline imploding Falcons in recent weeks.

Prediction: Colts 23, Falcons 20

St. Louis at Baltimore (-1)

Jeff Haynes/Associated Press

This one won't make for great television by any means, but bettors can find some good value. 

Even with the St. Louis Rams announcing backup Case Keenum will get the start against the Baltimore Ravens, Las Vegas refuses to go in heavy behind the home team.

For good reason, too—the Rams might have circled this game on the calendar as a time to make the switch. And why not? The miserable Baltimore defense has allowed two or more touchdown passes to quarterbacks in seven games this year, including five in a row.

The overwhelming narrative around the Rams, as noted by NFL Network's Ian Rapoport, is that they simply need a spark:

Baltimore could help them provide it, especially if Todd Gurley and his 709 yards and five touchdowns can get going on the ground. Remember, the Ravens just dropped a contest to the Jacksonville Jaguars at home to hit 2-7 while letting up two passing touchdowns and 90 rushing yards on just 22 attempts.

St. Louis has the ground attack and a stingy defense capable of pulling off the road victory. No matter how the line out of Las Vegas shifts, don't call it an upset.

Prediction: Rams 17, Ravens 10

San Francisco at Seattle (-13.5)

Bettors might think they have this one easy because the Seattle Seahawks traveled to San Francisco in Week 7 and stole a 20-3 victory from the 49ers, but much has changed in a short time.

To hit both major points quickly, the Seattle defense just coughed up a season-high 39 points in a loss to the Arizona Cardinals. San Francisco, meanwhile, promoted backup Blaine Gabbert to starter and he threw for 185 yards with a pair of touchdowns and interceptions in an upset of the Falcons.

San Francisco coach Jim Tomsula confirmed before the bye week that Gabbert would remain the starter, according to Rick Eymer of the Associated Press.

"I've known Blaine Gabbert from the time he came to the 49ers until now," Tomsula said. "He's done a wonderful job. He's a professional. He works hard and takes coaching to heart."

That's an extra week of prep for the now-confident 49ers, all while Seattle was busy losing at home while Carson Palmer tossed three touchdowns and Arizona rushed for 117 yards.

Seattle will still win this game because it's the better team. Gabbert will make a few mistakes and Marshawn Lynch will once again have an easy time after rushing for 122 yards and a score in the first contest.

Just don't expect it to be a blowout now that the 49ers actually have something that resembles a passing attack.

Prediction: Seahawks 27, 49ers 20

Stats courtesy of NFL.com and accurate as of Nov. 16. All advanced metrics courtesy of Pro Football Focus.