Deion Sanders Gets Biggest Win as Colorado Upsets Houston, Top Box Score Player Stats & Highlights

Amid growing speculation that he could be on the hot seat, Deion Sanders led Colorado to its first signature win of the season with a 42-32 upset victory over No. 14 Houston in Boulder on Friday night.

The Buffaloes pulled off the win thanks to 249 rushing yards and five touchdowns on the ground. Richard Young led the charge with 99 yards and two scores on 21 attempts.

Player	COMP-ATT	Pass Yds	TD	INT
C. Weigman, QB (Houston)	26-42	272	3	1
I. Wilson, QB (Colorado)	17-25	217	1	1
Player	Rush Att	Rush Yds	TD	Long
Richard Young, RB (Colorado)	21	99	2	38
DeKalon Taylor, RB (Colorado)	1	67	1	67
JaQuail Smith, RB (Colorado)	6	44	1	32
Kaneal Sweetwyne, RB (Colorado)	1	14	1	14
Makhi Hughes, RB (Houston)	15	106	1	29
Player	Rec	Rec Yds	TD	Long
Patrick Overmyer, WR (Houston)	9	116	1	24
Joseph Williams, WR (Colorado)	5	80	1	53

The victory for Colorado was its first over a team ranked in the top 15 of the Associated Press poll since 2007. It was also the program's first win over any ranked opponent since defeating No. 22 Iowa State on Oct. 11, 2025.

Houston looked like it was going to dominate early with its first two drives consisting of 28 plays and eating nearly 13 minutes of game time. Makhi Hughes capped off the second drive with a seven-yard touchdown run to make it 10-0.

Colorado responded with touchdowns on three of its four possessions in the second quarter to take a 21-20 lead going into halftime. Young started the scoring barrage with a 38-yard run.

DeKalon Taylor had the longest play of the game with a 67-yard touchdown run on a third-down option run late in the first half.

The third quarter started ugly for both teams with Isaac Wilson throwing an interception on the first play from scrimmage, but Colorado got the ball right back thanks to Randon Fontenette's strip sack of Houston quarterback Conner Weigman.

Colorado took advantage of the turnover with a touchdown on its ensuing possession. It added another score later in the quarter on Kaneal Sweetwyne's 14-yard touchdown to take a 35-20 lead.

The Colorado defense was terrific in the third quarter by forcing two turnovers, a turnover on downs and a punt to keep the Cougars off the board.

Houston's attempt at a fourth-quarter rally came up short because after Weigman's 24-yard touchdown pass to Patrick Overmyer, the two-point attempt failed to keep it a two-possession game at 35-26.

Colorado came right back with a 75-yard touchdown drive capped off by Young's second score of the night to get the lead back up to 16.

The win moves Colorado to 4-6 overall this season with two games remaining to become bowl eligible. It will go on the road next week to take on Cincinnati.

Houston's playoff hopes likely came to an end with this loss, but head coach Willie Fritz will look to get his team back on track against West Virginia on Nov. 21.