2026 Week 10 College Football Predictions for Every Game

Buckle your seatbelts, my friends, because Week 10 is an absolute thrill ride.

To kick off the final month of the 2026 regular season, Saturday's action features six games between Top 25 teams. Four of those clashes are within the SEC, and the others are a pair of classic rivalries.

Early on, it's the Holy War between BYU and Utah. Then, in the evening, Miami and Notre Dame square off in South Bend.

Block out the entire day—at least as much as you can—to watch a pivotal week for conference standings and the College Football Playoff race.

Rankings are based on the CFP Top 25.

ACC | American | Big 12 | Big Ten | CUSA | MAC | Mountain West | Pac-12 | SEC | Sun Belt | Top Matchups for Week 10

Top Matchups for Week 10

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Malachi Toney

No. 9 BYU (7-1) at No. 3 Utah (8-0), Noon ET

Despite being unbeaten, Utah has committed two turnovers in four straight outings. That, at the very least, is a concerning trend opposite BYU, which has nabbed two takeaways in five games. Still leaning toward the hosts because of a stout defense, but Utah's path to a first-season loss is evident.

Prediction: Utah 27, BYU 23

No. 5 Alabama (6-2) at No. 14 LSU (6-2), 3:30 p.m.

As the competition level has risen, the efficiency of Alabama's offense has sharply declined. LSU, meanwhile, ranks fourth nationally, allowing 4.3 yards per snap. The unit presents a huge challenge for Bama—especially on the road—and could send the Crimson Tide to the wrong side of the CFP bubble.

Prediction: LSU 29, Alabama 24

No. 6 Kentucky (7-1) at No. 13 Tennessee (6-2), 6:15 p.m.

Kentucky has been a tremendously fun story this season, not in the least because of its dramatic wins over South Carolina and LSU. Part of UK's surge has been an impressive ability to create takeaways on defense, leading to easy—and essential—points. Tennessee, though, has posted a plus-five turnover margin in home SEC games against Texas, Auburn and Alabama. That's a real obstacle for UK.

Prediction: Tennessee 26, Kentucky 20

No. 1 Miami (8-0) at No. 11 Notre Dame (7-1), 7:30 p.m.

Miami's defense has been slipping lately. Injuries have hampered the unit all season. Notre Dame is dealing with several significant absences on that side of the ball, too. In short: Expect some fireworks. Miami should score plenty of points, but giving up a stream of 20-yard gains is bound to bite the 'Canes eventually.

Prediction: Notre Dame 31, Miami 27

No. 2 Georgia (7-1) at No. 10 Ole Miss (6-2), 7:30 p.m.

Will the home/road Ole Miss splits hold true? So far, the Rebels have kept three visitors (LSU, Missouri and Auburn) to 350 yards and 24 points or less while defeating each one. On the road, they've struggled to stop Florida and Texas, with only a victory at Vanderbilt. Georgia is good enough defensively to win anywhere, but a shaky offensive night against a hosting Ole Miss team may be crushing.

Prediction: Ole Miss 28, Georgia 23

ACC Games

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Kevin Jennings

Virginia Tech (6-2) at SMU (6-2), Friday, 7 p.m. ET

SMU's last-second loss at Syracuse has complicated its postseason dreams, but a bounce-back night against Virginia Tech would be a solid win. As long as SMU's stingy money-down defense holds up, the Mustangs will stay in the ACC hunt.

Prediction: SMU 31, Virginia Tech 24

Clemson (5-3) at Syracuse (4-4), Noon
Prediction: Syracuse 26, Clemson 20

Florida State (3-5) at Boston College (4-4), Noon
Prediction: Florida State 31, BC 21

North Carolina (4-4) at Connecticut (4-4), Noon
Prediction: UNC 34, UConn 24

Duke (6-2) at North Carolina State (4-4), 12:30 p.m.
Prediction: Duke 27, NC State 20

Merrimack at No. 16 Wake Forest (7-1), 3:30 p.m.
Prediction: Wake Forest 56, Merrimack 7

No. 1 Miami (8-0) at No. 11 Notre Dame (7-1), 7:30 p.m.
Prediction: Notre Dame 31, Miami 27 (Top Matchups)

Louisville (5-3) at Georgia Tech (2-6), 7:30 p.m.
Prediction: Louisville 41, Georgia Tech 24

Big Ten Games

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Ty Dieffenbach and Wayne Knight

No. 8 UCLA (8-0) at Minnesota (5-3), Noon ET

UCLA has stayed undefeated on the strength of its defense, which has held six opponents below 300 yards. Minnesota isn't exactly an offensive juggernaut, either, ending four straight games below the mark. Yet the Gophers are 2-2 in that stretch anyway, holding home-field advantage against Michigan and Iowa in low-scoring games. UCLA is squarely on upset alert.

Prediction: Minnesota 17, UCLA 16

Nebraska (5-3) at Illinois (5-3), Friday, 8 p.m. ET
Prediction: Illinois 28, Nebraska 24

Maryland (2-6) at Purdue (3-5), 12:30 p.m.
Prediction: Purdue 34, Maryland 30

No. 23 Oregon (5-3) at No. 12 Ohio State (6-2), 3:30 p.m.
Prediction: Ohio State 26, Oregon 17

Penn State (4-4) at Washington (5-3), 3:30 p.m.
Prediction: Washington 27, Penn State 20

Rutgers (2-6) at Wisconsin (5-3), 4:15 p.m.
Prediction: Wisconsin 28, Rutgers 14

No. 19 Iowa (6-2) at Northwestern (6-2), 7:30 p.m.
Prediction: Northwestern 27, Iowa 23

Michigan State (2-6) at Michigan (5-3), 7:30 p.m.
Prediction: Michigan 24, MSU 9

Big 12 Games

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J'Koby Williams

West Virginia (5-3) at No. 15 Texas Tech (7-1), 9:30 p.m. ET

Michael Hawkins Jr. has been among the most exciting players in the country this season, totaling 2,434 yards and 27 touchdowns for West Virginia. The problem is that, aside from a recent win against a mediocre TCU offense, WVU cannot stop anyone. Tough to see that changing here.

Prediction: Texas Tech 44, WVU 31

TCU (4-4) at No. 22 Arizona (6-2), Friday, 10:15 p.m.
Prediction: Arizona 24, TCU 16

No. 9 BYU (7-1) at No. 3 Utah (8-0), Noon
Prediction: Utah 27, BYU 23 (Top Matchups)

Iowa State (4-4) at Baylor (5-3), Noon
Prediction: Baylor 34, Iowa State 27

Oklahoma State (5-3) at Kansas State (4-4), 1 p.m.
Prediction: Oklahoma State 30, Kansas State 24

Cincinnati (5-3) at No. 17 Houston (6-2), 3:30 p.m.
Prediction: Houston 37, Cincinnati 28

UCF (4-4) at Kansas (3-5), 3:45 p.m.
Prediction: Kansas 26, UCF 21

Colorado (3-5) at Arizona State (4-4), 7:30 p.m.
Prediction: ASU 24, Colorado 20

SEC Games

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Jamal Roberts

No. 7 Texas (6-2) at No. 18 Missouri (6-2), Noon

Texas has clawed out a few tight victories despite some obvious issues on offense. Arch Manning is terribly inconsistent. The running game is inefficient behind a subpar blocking group. Missouri, which has been a thorn defensively, has a great opportunity to throw a dagger into Texas' fading championship vision.

Prediction: Missouri 24, Texas 23

Arkansas (3-5) at Auburn (4-4), 12:45 p.m.
Prediction: Auburn 35, Arkansas 20

Texas A&M (4-4) at No. 21 South Carolina (5-3), 3 p.m.
Prediction: South Carolina 27, Texas A&M 23

No. 5 Alabama (6-2) at No. 14 LSU (6-2), 3:30 p.m.
Prediction: LSU 29, Alabama 24 (Top Matchups)

Vanderbilt (3-5) at Mississippi State (4-4), 4:15 p.m.
Prediction: Mississippi State 30, Vanderbilt 21

No. 6 Kentucky (7-1) at No. 13 Tennessee (6-2), 6:15 p.m.
Prediction: Tennessee 26, Kentucky 20 (Top Matchups)

No. 2 Georgia (7-1) at No. 10 Ole Miss (6-2), 7:30 p.m.
Prediction: Ole Miss 28, Georgia 23 (Top Matchups)

Oklahoma (4-4) at No. 24 Florida (5-3), 7:45 p.m.
Prediction: Florida 24, Oklahoma 17

American Games

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Ryder Burton

UTSA (7-1) at Florida Atlantic (5-3), Thursday, 7:30 p.m. ET
Prediction: UTSA 45, FAU 41

South Florida (6-2) at East Carolina (4-4), Friday, 7:30 p.m.
Prediction: USF 23, ECU 20

Tulsa (4-4) at Tulane (4-4), Noon
Prediction: Tulane 27, Tulsa 23

Charlotte (1-7) at UAB (4-4), 3:30 p.m.
Prediction: UAB 31, Charlotte 17

Temple (2-6) at Navy (2-6), 3:30 p.m.
Prediction: Navy 28, Temple 24

Rice (1-7) at North Texas (6-2), 4 p.m.
Prediction: North Texas 48, Rice 21

Air Force (6-2) at Army (5-3), 7:30 p.m.
Prediction: Army 24, Air Force 20

Conference USA Games

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JJ Kohl

Delaware (4-4) at Kennesaw State (2-6), 3 p.m.
Prediction: Kennesaw State 30, Delaware 27

Western Kentucky (3-5) at Middle Tennessee (4-4), 3:30 p.m.
Prediction: WKU 28, MTSU 24

Missouri State (3-5) at Florida International (3-5), 4 p.m.
Prediction: FIU 31, Missouri State 21

Sam Houston (1-7) at Jacksonville State (6-2), 7 p.m.
Prediction: Jax State 35, Sam Houston 17

Liberty (7-1) at New Mexico State (3-5), 8 p.m.
Prediction: Liberty 34, NMSU 16

MAC Games

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Riley Neer

Ohio (6-2) at Akron (1-7), Tuesday, 7 p.m. ET
Prediction: Ohio 33, Akron 17

Buffalo (5-3) at Miami (5-3), Tuesday, 8 p.m.
Prediction: Miami 29, Buffalo 24

Ball State (3-5) at Massachusetts (4-4), Wednesday, 7 p.m.
Prediction: UMass 27, Ball State 23

Toledo (6-2) at Sacramento State (2-7), Wednesday, 7 p.m.
Prediction: Toledo 37, Sac State 14

Central Michigan (3-5) at Eastern Michigan (4-5), Wednesday, 7:30 p.m.
Prediction: EMU 22, CMU 19

Mountain West Games

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Kiefer Sibley

New Mexico (7-1) at Nevada (3-5), Friday, 9 p.m. ET
Prediction: New Mexico 27, Nevada 13

Northern Illinois (0-8) at San Jose State (4-5), 4 p.m.
Prediction: SJSU 31, NIU 17

Air Force (6-2) at Army (5-3), 7:30 p.m.
Prediction: Army 24, Air Force 20

Hawaii (2-6) at UTEP (1-7), 9:30 p.m.
Prediction: Hawaii 28, UTEP 23

Wyoming (5-3) at UNLV (5-3), 10:30 p.m.
Prediction: UNLV 26, Wyoming 24

Pac-12 Games

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Dylan Riley

No. 25 Boise State (7-1) at Colorado State (3-5), 6 p.m.
Prediction: Boise State 38, CSU 27

Fresno State (5-3) at Utah State (3-5), 9:30 p.m.
Prediction: Fresno State 24, Utah State 20

Texas State (4-4) at Oregon State (5-3), 10:30 p.m.
Prediction: Oregon State 47, Texas State 42

Sun Belt Games

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Jalen Mickens and Eli Finley

James Madison (7-2) at Southern Miss (3-5), Thursday, 8 p.m. ET
Prediction: JMU 34, Southern Miss 27

Old Dominion (2-7) at Coastal Carolina (3-5), 1 p.m.
Prediction: Coastal Carolina 23, ODU 20

Georgia State (4-4) at Appalachian State (5-3), 2:30 p.m.
Prediction: App State 31, Georgia State 24

Louisiana-Monroe (1-7) at Arkansas State (4-4), 3 p.m.
Prediction: Arkansas State 37, ULM 21

Marshall (5-3) at Georgia Southern (4-4), 3:30 p.m.
Prediction: Georgia Southern 30, Marshall 24

Louisiana Tech (6-2) at Troy (4-4), 4 p.m.
Prediction: La Tech 27, Troy 20

South Alabama (4-4) at Louisiana (5-3), 5 p.m.
Prediction: Louisiana 33, South Alabama 23