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DENVER, CO - SEPTEMBER 23:  Cornerback DJ Hayden #25 of the Oakland Raiders reacts after a Denver Broncos first down during the third quarter at Sports Authority Field Field at Mile High on September 23, 2013 in Denver, Colorado. The Broncos defeated the Raiders 37-21. (Photo by Justin Edmonds/Getty Images)
DENVER, CO - SEPTEMBER 23: Cornerback DJ Hayden #25 of the Oakland Raiders reacts after a Denver Broncos first down during the third quarter at Sports Authority Field Field at Mile High on September 23, 2013 in Denver, Colorado. The Broncos defeated the Raiders 37-21. (Photo by Justin Edmonds/Getty Images)Justin Edmonds/Getty Images

What Are the NFL's Most Devastating Injuries?

Dave Siebert, M.D.Jun 4, 2014

They are the phrases no NFL fan wants to hear during a TV or radio broadcast.

"Player X is shaken up."

"Player Y is slow to get up."

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"Here comes the cart."

Next comes the waiting. The Twitter rumors. The MRI results.

Then, finally, a projected recovery time.ย 

PHILADELPHIA, PA - SEPTEMBER 15: Wide receiver Malcom Floyd #80 of the San Diego Chargers is wheeled off the field and to a local hospital after sustaining a neck injury during the third quarter against the Philadelphia Eagles during a game at Lincoln Fin

NFL injuries come in many shapes and sizes, ranging from minor bumps and bruises to bona fide career-threatening conditions. The former may limit a player minimally, while the latter can sideline him indefinitely.

When a team announces a player's ultimate diagnosisโ€”or when it leaks to the pressโ€”many fans will look immediately for the rehab timeline. All too often, that timeline surpasses the remainder of the season.

Yet the story doesn't end there. Following a serious injury, medical staffs must utilize precise medical, surgical and physical therapy treatment regimens as well as strict rehabilitation protocols before the injured player can safely return to play.

Much of the time, that playerโ€”with the help of the outstanding medical personnel throughout the NFLโ€”will eventually make a triumphant return to the field.

But not always.

Some injuries, even with the best medical care by the best medical professionals, can carry a shaky prognosis.ย Rare complicationsโ€”surgical infections, for exampleโ€”can also muddy the picture. For simplicity's sake, this article leaves them for another conversation. It also will not discuss some of the specialized orthopedic injuries in an effort to keep a broader perspective.

With that in mind, let's take a look at some of the NFL's most potentially devastating injuries.

The Multi-Ligament Knee Injury or Dislocation

Regrettably, ACL tears dot NFL news feeds on a somewhat regular basis.

HOUSTON, TX - AUGUST 17:  Dustin Keller#81 of the Miami Dolphins sits on the f1eld after a rough tackle in the first half against the Houston Texans during a preseaon game at Reliant Stadium on August 17, 2013 in Houston, Texas.  (Photo by Scott Halleran/

Contact ACL injuries often occur when another player hits the knee of a planted leg. Non-contact injuries can arise from a sharp-but-awkward plant and cut that leads to a mismatch of momentum and joint mechanicsโ€”one strong enough to overwhelm the ligament.

The result? An unstable kneeโ€”one that makes playing in the NFL all but impossible.

ACL tears frequently come with simultaneous injury to one or more of the other main knee ligaments, a meniscusโ€”the shock-absorbing cartilage cushions within the knee jointโ€”or both.

Miraculously, thanks to surgeons like Dr. James Andrews and others throughout the country, such a seemingly disastrous injury constellation no longer represents an automatic threat to a career. In rare cases, it does not even necessarily end a player's upcoming season if it occurs early enough in the year.

Even so, some knee-injury combinations can prove especially devastating.ย For example, knee dislocationsโ€”where the joint surfaces of the femur and tibia separateโ€”constitute true orthopedic emergencies and require immediate action.

The ACL runs through the center of the knee and prevents it from over-twisting inward.

When a knee dislocates, the shifting bones can threaten other structures within the jointโ€”not to mention the ACL, PCL, MCL and LCL. In extreme cases, a dislocation can compress or tear the popliteal arteryโ€”the main blood supply of the lower legโ€”as it runs through the knee. Unless a doctor setsโ€”or "reduces"โ€”the dislocation, the compromised blood flow can cause tissue damage or death beyond the site of the injury.

Furthermore, outward-directed dislocations can stretch and damage the common peroneal nerveโ€”the nerve responsible for controlling sensation and movement in the lower leg.

Fortunately, knee dislocations in the highest levels of football remain rareโ€”though they do exist. When they occur, the complicated and lengthy rehab, shear extent of damage and potential for setbacks, long-term complications or incomplete healing make for quite the uphill battle.

COLUMBIA, SC - OCTOBER 27: Marcus Lattimore #21 of the South Carolina Gamecocks covers his head after injuring his knee against the Tennessee Volunteers during the game at Williams-Brice Stadium on October 27, 2012 in Columbia, South Carolina. (Photo by J

In Oct. 2012, former University of South Carolina running back Marcus Lattimore suffered a right knee dislocationโ€”one that, according to Sports Illustrated's Andy Staples,ย tore his ACL, PCL and LCL.

The San Francisco 49ers drafted Lattimore in 2013. He is still recovering, but according to Matt Barrows ofย The Sacramento Bee, he is taking part in 49ers OTAs.

Former Los Angeles Raiders fullback Napoleon McCallum was not so lucky.

As Jerry Crowe wrote in 2010 forย The Los Angeles Times, McCallum tore three ligaments in his knee and "suffered nerve and artery damage" in addition to muscle injuries. He never played in the NFL again. With today's advancing medical care and surgical technique, such a heartbreaking scenario is hopefully becoming less and less likely.

Intra-Abdominal or Intra-Thoracic Injuries

Compared to joint or muscle injuries, internal organ damage occurs infrequently in football. However, for somewhat obvious reasons, any such injury can turn dire very quickly

When it comes to abdominal injuries, the wrong hit at the wrong angleโ€”in the wrong place at the wrong timeโ€”is usually to blame.ย Direct blows to the midsection can injure the spleen or other abdominal organs, while strong hits to the chest can bruise the lungs.

SEATTLE, WA - AUGUST 29: Cornerback DJ Hayden #25 of the Oakland Raiders warms up prior to the game against the Seattle Seahawks at CenturyLink Field on August 29, 2013 in Seattle, Washington. (Photo by Otto Greule Jr/Getty Images)

For instance, in 2012, Dallas Cowboys tight end Jason Witten suffered a lacerated spleen at the hands of Oakland Raiders linebacker Rolando McClain. He did not need surgery, but in the case of an outright splenic rupture, a surgeon may need to perform a splenic artery embolizationโ€”purposefully cutting off an artery to stop the bleedingโ€”or a complete splenectomy.

More recently, current Oakland Raiders cornerback D.J. Hayden recovered from a hit to the torso that nearly completely severed his inferior vena cavaโ€”the large vein that collects all of the blood from the lower body and brings it back to the heart. The injury nearly took is lifeโ€”and probably should haveโ€”and Hayden's recovery remains one of the most impressive injury comebacks in recent memory.

The chest can also fall victim to serious injury. Last season saw a small flurry of pulmonary contusionsโ€”or lung bruises. Cleveland Browns linebacker Barkevious Mingo missed the early part of the 2013 season after suffering the injury in August.

Thankfully, Mingo recovered relatively quickly and still played in 15 games last season.

This X-ray shows findingsโ€”white haziness on the left side, the patient's right lungโ€”that may represent a pulmonary contusion. On the left side (the patient's right lung).

The severity of pulmonary contusions ranges widelyโ€”from insignificant to life-threateningโ€”depending on the extent of lung involved, but a player with a contusion must usually rest until it fully resolves. A second contusion on top of a not-yet-healed injury could turn a minor respiratory issue into a suffocating oneโ€”literally.

This diagram shows the location of the first rib (red).

Elsewhere, Ben Roethlisberger's 2012 first rib dislocation probably surprised many health care professionals across the country. A first rib dislocation occurs incredibly rarelyโ€”and typically in situations like motor-vehicle accidents, not football games.

Roethlisberger's unstable first rib threatened his aortaโ€”the body's largest artery that leaves the heart to delivery blood to the rest of the body.

Somewhat similarly, in 2013, Minnesota Vikings quarterback Christian Ponder missed a start due to a broken rib in close proximity to his heart. If another hit displaced the fracture further inward, the injury could have threatened his heart or the surrounding vasculature.

Major Leg Muscle Tendon Ruptures

Broadly speaking, a tendon attaches a muscle body to bone. When the muscle contracts, it pulls on the tendonโ€”which in turn pulls on the boneโ€”producing movement.

Tendons somewhat resemble a rubber band. They can stretch to a certain degree, but if a tackle forces one to extend beyond its capacity, it can rupture and pull away from the bone.

The Achilles tendonโ€”seen here as a thick white bandโ€”connects the calf muscles to the back of the heel, allowing an athlete to plantarflex (point his or her toes).

For example, if an athlete forcefully plants his toes behind him while another athlete pushes him back and causes him to drive his heel to the ground, the Achilles tendon can pull off the back of the heel.

Most medical staffs elect to surgically reattach an Achilles tendon to the bone following a tear. The rehabilitation process is often successful, but it is also lengthyโ€”almost always ending the player's season. He must slowly work back into shape by placing gradually increasing amounts of stress on the healing tissue during his recovery.

New England lineman Vince Wilfork is still rehabbing his Achilles tendon injury from September of last year.

Similar to Achilles injuries, hamstring tendon ruptures all but certainly end a player's seasonโ€”as do quadriceps and patellar tendon tears. Each has its own unique set of challenges to overcome, and if a player cannot return to full strength, his performance will suffer.

Free-agent linebacker Desmond Bishop missed the entire 2012 season following a hamstring tendon rupture, likely leading to his 2013 release from the Green Bay Packers. He then had a brief stint with the Minnesota Vikings before tearing his ACL.

The relationship of Desmond's injuries is not clear, though at least one studyโ€”published in The American Journal of Orthopedics by Mansour and colleaguesโ€”suggests proximal hamstring tendon ruptures might be a harbinger of "elite-level physical deterioration." The study is a retrospective review of a small sample of playersโ€”both significant limitationsโ€”but it is worth noting.

Severe Cervical Spine Injuries

A few times per season, an NFL player goes down after a helmet-to-helmet collision, and the crowd falls silent. Football comes to a pause, and the thoughts of the football community turn to the fallen player's well-being.

After severe neck trauma, a player can experience brief loss of sensation or paralysisโ€”a process known as neurapraxia. It usually resolves, but following theย injury, fluid can collect in the spinal canal and place pressure on the spinal cordโ€”a process known as a spinal-cord contusion.ย If contusion symptoms such as numbness, weakness or pain persist, a player may decide to undergo a spinal fusionโ€”similar to current free-agent tight end Jermichael Finley in 2013.

In the worst-case scenario, a hit directly damages the spinal cord directly via a displaced vertebral fracture. Thankfully, such a catastrophic injury is quite rareโ€”but not unheard of. In 2010, a hit to the head and neck tragically paralyzed former Rutgers University defensive tackle Eric Legrand.

As Finley knows, receiving medical clearance following a severe neck injury can be a difficult and lengthy process. The stability of his neck and size of his spinal canal fall under the microscopeโ€”as does his entire neurological exam. Any abnormalities or lingering problems can tip the risk-versus-reward balance much too far in the wrong direction.

Multiple Concussions

Even with the ever-intensifying focus on concussions, one such injury may fall by the wayside without much thoughtโ€”as may a second and even a third.

However, players with a history of multiple concussionsโ€”such as Jay Cutler and Michael Vick, among many othersโ€”face a special set of circumstances.

Though concussion research and science are still in their relative infancy, many physicians believe that with each concussion, symptoms can become more severe and may last longerโ€”not to mention the still-unclear long-term consequences of multiple head injuries. Each concussion may also make it easier to suffer another injury in the future.

That said, every concussion is unique, and generalizing one player's history to another's is inappropriate.

Recently, former Buffalo Bills quarterback Kevin Kolb suffered an apparently career-threatening concussionโ€”the latest of multiple injuries in his past. He landed on injured reserve shortly thereafter, and as of now, his return remains in doubt. He remains a free agent.

Former Detroit Lions running back Jahvid Best went through a similar sequence of events. Multiple concussionsโ€”stemming back to collegeโ€”eventually led to doctors feeling uncomfortable giving him medical clearance to take the field once again. The Lions released the former University of California standout in June of last year.

Dr. Dave Siebert is a resident physician at the University of Washington who plans to pursue fellowship training in Primary Care (non-operative) Sports Medicine. The medical discussion above is for informational purposes only.

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