The title picture shifts with each passing week, and currently it is Chelsea who top the table with only 10 games left to play.
With Manchester City on League Cup duty and Arsenal combusting at the hands of Stoke City, the big winners of Week 28 were Jose Mourinho's Blues, who collected all three points away at neighbours Fulham.
The victory lifted Chelsea four points clear at the top of the Premier League summit, per BBC Sport, a gap they will want to extend when they face Tottenham.
The fixture list is once again reduced this weekend, this time because of the scheduled FA Cup matches. Here is a full list of the Premier League games for Week 29, with kick-off times and result predictions as well as a focus on the biggest matches of the weekend:
|Premier League Week 29 Fixtures and Predictions|
|West Brom v Manchester United||March 8||12:45 p.m.||1-2|
|Cardiff City v Fulham||March 8||3 p.m.||1-2|
|Crystal Palace v Southampton||March 8||3 p.m.||1-1|
|Norwich v Stoke City||March 8||3 p.m.||2-0|
|Chelsea v Tottenham Hotspur||March 8||5:30 p.m.||3-1|
Chelsea v Tottenham
The big match of the weekend is undoubtedly Tottenham's visit to Stamford Bridge to tackle league leaders Chelsea. Spurs have managed to steady a shaking ship under the tenure of Tim Sherwood and are challenging hard for a Champions League spot for next season.
Goals were a huge problem under the previous management, but with the reintroduction of Emmanuel Adebayor, results have improved.
However, Spurs still only have a goal difference of plus-four, per Squawka, and this could see them lose a place or two come the end of the season.
Chelsea have returned to old ways under the tutelage of Mourinho since his return from Real Madrid. The organised Mourinho tactics have returned as Chelsea mix consistent function with a touch of flair.
Arsene Wenger has already confirmed he feels it will be difficult to catch Chelsea, as tweeted by Sky Sports journalist Pete O'Rourke:
A quick-fire hat-trick from Andre Schurrle sealed the points against Fulham and took full advantage of Arsenal's inability to collect anything at Stoke.
It is looking ominous for the Premier League's contenders as Mourinho's know-how starts to visibly kick into effect. His teams know how to win, and he is the ultimate winner when it comes to finding a strategy to capture trophies.
As well as Spurs have done of late, they will not get any change out of this Chelsea team, and the brilliance of Eden Hazard and Oscar should see the Blues over the line once again.
Prediction: Chelsea win 3-1
West Brom v Manchester United
West Brom have the worst win ratio in the Premier League this term, having recorded only four wins all season, per Squawka.
Amazingly, their one away victory of the season came at Old Trafford when they beat Manchester United 2-1.
Defeat has become a repeated event for United manager David Moyes, whose team is hemorrhaging goal after goal in a forgettable season.
United face a stressful race for a Europa League spot, which is far from assured. The game at The Hawthorns is a must-win match for them.
Moyes will be thankful that his big guns are back now. He can call on Robin van Persie and Wayne Rooney as well as new purchase Juan Mata. But their influence is yet to be felt, as United still stutter for results.
West Brom manager Pepe Mel is also feeling the heat, as his side sit just outside the relegation zone. A loss to United could put his job at further risk as the club try to avoid slipping into the Championship.
Despite their troubles this season, United should edge this affair and gain a modicum of revenge for their embarrassing home defeat earlier in the season.
Prediction: Man Utd win 2-1
Cardiff City v Fulham
It has been an incredibly hard season for both clubs this year, with negative events on and off the pitch. Cardiff and Fulham are almost cut adrift at the bottom of the Premier League, and this match has become both teams' Cup Final.
Cardiff have struggled in their first season back in the top division, managing to net only 19 times all year, per Squawka.
Fulham have brought in legendary German manager Felix Magath to rescue them from certain doom, but it is not looking good for the West London outfit.
This match will likely determine which team goes down and which will have a vital lifeline in the coming weeks.
Cardiff's inability to score could ultimately prove their downfall as Fulham look to gain some leverage under their new coach.
Magath has the likes of Darren Bent and Kostas Mitroglou at his disposal, and if he can get them firing, their Premier League stay may not be over.
Prediction: Fulham win 2-1