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PASADENA, CA - OCTOBER 8: UCLA Bruins quarterback Dorian Thompson-Robinson (1) runs with the ball during the college football game between the Utah Utes and the UCLA Bruins on Saturday, October 8, 2022 at the Rose Bowl in Pasadena, CA. (Photo by Ric Tapia/Icon Sportswire via Getty Images)
PASADENA, CA - OCTOBER 8: UCLA Bruins quarterback Dorian Thompson-Robinson (1) runs with the ball during the college football game between the Utah Utes and the UCLA Bruins on Saturday, October 8, 2022 at the Rose Bowl in Pasadena, CA. (Photo by Ric Tapia/Icon Sportswire via Getty Images)Dorian Thompson-Robinson | Ric Tapia/Icon Sportswire via Getty Images

College Football Picks: Week 8 Predictions for Every Game

David KenyonOct 19, 2022

The midpoint of the 2022 season is a natural place to recalibrate expectations, but Week 8's schedule is also a fun juxtaposition.

Looking at the Top 10, eight programs are in action with one showdown between them—hello, UCLA and Oregon—three others meeting a ranked opponent and one more traveling to a program just outside the Top 25. The best matchups of the weekend are really good.

On the other hand, eight ranked teams have an idle Saturday. They're taking a much-needed break—typically the only one during the regular season—and readying for the rest of the year.

That's the long version of saying it's a top-heavy weekend around the sport. Whenever we think something like that, though, the football gods seemingly stir up the chaos.

And, as always, we're totally here for that.

AP Nos. 25-21

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TAMPA, FLORIDA - OCTOBER 15: Michael Pratt #7 of the Tulane Green Wave passes during a game against the South Florida Bulls at Raymond James Stadium on October 15, 2022 in Tampa, Florida. (Photo by Mike Ehrmann/Getty Images)
TAMPA, FLORIDA - OCTOBER 15: Michael Pratt #7 of the Tulane Green Wave passes during a game against the South Florida Bulls at Raymond James Stadium on October 15, 2022 in Tampa, Florida. (Photo by Mike Ehrmann/Getty Images)

Memphis (4-3) at No. 25 Tulane (6-1), 3:30 p.m. ET

Tulane has quietly pulled into the Top 25 for the first time in 24 years. Next up is a clash with high-scoring Memphis, which has posted 35.6 points per game. Tulane needs a bounce-back performance from its secondary, but Michael Pratt—who's totaled 300-plus yards and three-plus touchdowns in consecutive weeks—should be able to pick apart Memphis through the air.

Prediction: Tulane 31, Memphis 27


No. 24 Mississippi State (5-2) at No. 6 Alabama (6-1), 7 p.m. ET

For prediction, see No. 6 Alabama.


No. 23 North Carolina State (5-2), Idle


No. 22 North Carolina (6-1), Idle


No. 21 Cincinnati (5-1) at SMU (3-3), Noon ET

Staying in the AAC, Cincinnati has a similar outlook this weekend. SMU scores a bunch of points but doesn't play a whole lot of defense. As long as Cincinnati limits an average SMU's rushing attack, an upset should not happen. But that's the path to a victory for SMU.

Prediction: Cincinnati 38, SMU 24

AP Nos. 20-16

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STATE COLLEGE, PA - OCTOBER 01: Nicholas Singleton #10 of the Penn State Nittany Lions celebrates with teammates after scoring a touchdown against the Northwestern Wildcats during the first half at Beaver Stadium on October 1, 2022 in State College, Pennsylvania. (Photo by Scott Taetsch/Getty Images)
STATE COLLEGE, PA - OCTOBER 01: Nicholas Singleton #10 of the Penn State Nittany Lions celebrates with teammates after scoring a touchdown against the Northwestern Wildcats during the first half at Beaver Stadium on October 1, 2022 in State College, Pennsylvania. (Photo by Scott Taetsch/Getty Images)

No. 20 Texas (5-2) at No. 11 Oklahoma State (5-1), 3:30 p.m. ET

For prediction, see No. 11 Oklahoma State.


No. 19 Kentucky (5-2), Idle


No. 18 Illinois (6-1), Idle


No. 17 Kansas State (5-1) at No. 8 TCU (6-0), 8 p.m. ET

For prediction, see No. 8 TCU.


Minnesota (4-2) at No. 16 Penn State (5-1), 7:30 p.m. ET

If quarterback Tanner Morgan (head) is unable to play, Minnesota will be short-handed. That said, Michigan just ran up, over, around and through Penn State last weekend—and Minnesota has Mohamed Ibrahim, one of the nation's top running backs. But the hosts, looking to recover from that embarrassing 41-17 loss, should be able to pull out a victory in their annual White Out game.

Prediction: Penn State 23, Minnesota 20

AP Nos. 15-11

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WINSTON-SALEM, NC - OCTOBER 08: Wake Forest Demon Deacons wide receiver A.T. Perry (9) catches a touchdown during a football game between the Army Black Knights  and the Wake Forest Demon Deacons on October 8, 2022, at Truist Field in Winston-Salem, NC. (Photo by Charles Brock/Icon Sportswire via Getty Images)
WINSTON-SALEM, NC - OCTOBER 08: Wake Forest Demon Deacons wide receiver A.T. Perry (9) catches a touchdown during a football game between the Army Black Knights and the Wake Forest Demon Deacons on October 8, 2022, at Truist Field in Winston-Salem, NC. (Photo by Charles Brock/Icon Sportswire via Getty Images)

No. 15 Utah (5-2), Idle


No. 14 Syracuse (6-0) at No. 5 Clemson (7-0), Noon ET

For prediction, see No. 5 Clemson.


Boston College (2-4) at No. 13 Wake Forest (5-1), 3:30 p.m. ET

The primary question is whether Boston College can keep up. Statistically speaking, the defenses are comparable. However, there's no question that Wake Forest's offense—from both the eye test and numbers—has performed at a much higher level than BC's unit.

Prediction: Wake Forest 37, Boston College 17


No. 12 USC (6-1), Idle


No. 20 Texas (5-2) at No. 11 Oklahoma State (5-1), 3:30 p.m. ET

Oklahoma State coach Mike Gundy refused to tell reporters if quarterback Spencer Sanders practiced on Monday, and that mindset is improbable to change prior to the weekend. Nevertheless, the pick is Texas either way. Texas is vulnerable through the air, but Sanders is dealing with a shoulder injury. A healthy Quinn Ewers wins out over a banged-up Sanders.

Prediction: Texas 34, Oklahoma State 24

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AP Nos. 10-6

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Oregon quarterback Bo Nix (10) runs the ball against Stanford during the first half of an NCAA college football game Saturday, Oct. 1, 2022, in Eugene, Ore. (AP Photo/Andy Nelson)
Oregon quarterback Bo Nix (10) runs the ball against Stanford during the first half of an NCAA college football game Saturday, Oct. 1, 2022, in Eugene, Ore. (AP Photo/Andy Nelson)

No. 9 UCLA (6-0) at No. 10 Oregon (5-1), 3:30 p.m. ET

Oregon hosts this battle of Pac-12 teams unbeaten in league play. To this point, UCLA's lone game outside of Los Angeles was against a woeful Colorado side. How the offense responds to a raucous environment will decide the game, because it's unlikely UCLA will contain a surging Oregon offense. Bo Nix has become a lethal dual-threat QB and traditionally plays well at home. UCLA is plenty capable of winning, but Oregon has the edge.

Prediction: Oregon 38, UCLA 34


No. 17 Kansas State (5-1) at No. 8 TCU (6-0), 8 p.m. ET

As usual, what should we expect from K-State? There are days of brilliance, like wrecking Missouri and Oklahoma, mixed with moments of immense frustration in a loss to Tulane or escape at Iowa State. TCU is finally throwing the ball to star wideout Quentin Johnston consistently and has prevented explosive runs all season. If the Horned Frogs continue doing both, they'll stay undefeated.

Prediction: TCU 27, Kansas State 20


No. 7 Ole Miss (7-0) at LSU (5-2), 3:30 p.m. ET

Other than hosting Kentucky, Ole Miss hasn't played a tough schedule. Plus, the Rebels certainly haven't faced a stadium as challenging as Death Valley. We're sticking with Ole Miss because of its powerful rushing attack opposite a shaky LSU defense, but don't let the ranked vs. unranked part of this matchup fool you: This is a remarkably even matchup.

Prediction: Ole Miss 27, LSU 24


No. 24 Mississippi State (5-2) at No. 6 Alabama (6-1), 7 p.m. ET

After seeing Tennessee shred Bama's secondary, the instinct may be to believe an Air Raid offense can do the same. Mississippi State, though, is built on executing quick-hitting passes with only nine throws of 30-plus yards. Alabama remains an overwhelming favorite in this matchup.

Prediction: Alabama 45, Mississippi State 17

AP Nos. 5-1

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COLUMBUS, OH - OCTOBER 01: Ohio State Buckeyes wide receiver Emeka Egbuka (2) runs with the ball after catching a pass during a college football game against the Rutgers Scarlet Knights on October 1, 2022 at Ohio Stadium in Columbus, Ohio. (Photo by Joe Robbins/Icon Sportswire via Getty Images)
COLUMBUS, OH - OCTOBER 01: Ohio State Buckeyes wide receiver Emeka Egbuka (2) runs with the ball after catching a pass during a college football game against the Rutgers Scarlet Knights on October 1, 2022 at Ohio Stadium in Columbus, Ohio. (Photo by Joe Robbins/Icon Sportswire via Getty Images)

No. 14 Syracuse (6-0) at No. 5 Clemson (7-0), Noon ET

We're about to learn a lot about Syracuse. While the Orange are a spectacular 6-0, they've also faced one of the easiest schedules in the country. Syracuse, at home, stuck with an unimpressive Clemson team last season. This time around, it's at the venue where Clemson—which is much improved offensively—has earned 37 straight wins. The streak lives.

Prediction: Clemson 31, Syracuse 21


No. 4 Michigan (7-0), Idle


Tennessee-Martin (4-2) at No. 3 Tennessee (6-0), Noon ET

In the aftermath of Tennessee's upset over Alabama, Vols fans carried the uprights out of the stadium. Keith Carver, the Chancellor at UT Martin, so kindly offered to host the game if Tennessee couldn't replace them in time. Worth a shot! UT Martin is ranked 18th in the FCS, so don't brush off the Skyhawks. Still, the Vols win handily.

Prediction: Tennessee 52, UT Martin 14


Iowa (3-3) at No. 2 Ohio State (6-0), Noon ET

Flip the location, and this contest feels more dangerous. Ohio State needs to avoid that mentality—we're not playing, after all—but Iowa's pitiful offense will be overwhelmed in Columbus. As long as the Buckeyes don't allow Iowa's defense to score, they'll cruise to a victory.

Prediction: Ohio State 41, Iowa 10


No. 1 Georgia (7-0), Idle

Best Unranked Clashes

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Toledo's Dequan Finn plays against Ohio State during an NCAA college football game Saturday, Sept. 17, 2022, in Columbus, Ohio. (AP Photo/Jay LaPrete)
Toledo's Dequan Finn plays against Ohio State during an NCAA college football game Saturday, Sept. 17, 2022, in Columbus, Ohio. (AP Photo/Jay LaPrete)

Troy (5-2) at South Alabama (5-1), Thursday, 7:30 p.m. ET

Early indications are Louisiana's reign over the Sun Belt West is coming to an end. South Alabama toppled the division's four-time reigning champ, sits at 2-0 in league play and hosts Troy—which is 3-1 in conference—for a pivotal game. Troy is a tempting pick on the strength of its defense, but South Alabama has showed a stronger offense lately. In a close one, USA takes a commanding lead in the West.

Prediction: South Alabama 23, Troy 21


Kansas (5-2) at Baylor (3-3), Noon ET

Kansas isn't a "desperate" team, but the Jayhawks are trying to avoid a three-game skid. Baylor, on the other hand, is nearing that label, as missing a bowl is suddenly a realistic possibility. While the secondary has become an issue for the reigning Big 12 champs, the KU defense has struggled over the last six quarters and now might be without key corner Cobee Bryant. Baylor picks up a much-needed result.

Prediction: Baylor 31, Kansas 26


Toledo (5-2) at Buffalo (4-3), 1 p.m. ET

You'll notice a theme here shortly. Entering the tilt, Toledo and Buffalo each hold a 3-0 record in MAC play. This could be a preview of the conference title game. Buffalo has home-field advantage, but its defense has ceded 6.3 yards per snap—a major concern opposite a sizzling Toledo offense led by Dequan Finn. The visitors snag a key league win.

Prediction: Toledo 38, Buffalo 30


North Texas (4-3) at UTSA (5-2), 3:30 p.m. ET

The programs are locked atop Conference USA with 3-0 league marks. One growing concern for North Texas, though, is the offense has turned only 56.3 percent of its red-zone opportunities into touchdowns. That's not going to cut it opposite UTSA, which certainly has revenge on the brain after UNT spoiled an undefeated record last season.

Prediction: UTSA 38, North Texas 31


Boise State (4-2) at Air Force (5-2), 7 p.m. ET

If you have a good handle on the Mountain West in 2022, that makes one of us. The conference has been loaded with confusing results. The apparent trend to know is Boise State has struggled on the road (1-2), whereas Air Force has excelled at home (4-0). But in a matchup of two talented, inconsistent teams, no result—either team winning in a tight game or blowout—would be surprising.

Prediction: Air Force 24, Boise State 21

Rest of the Slate, Part I

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LUBBOCK, TEXAS - SEPTEMBER 10: Quarterback Donovan Smith #7 of the Texas Tech Red Raiders passes the ball during the first half of the game against the Houston Cougars at Jones AT&T Stadium on September 10, 2022 in Lubbock, Texas. (Photo by John E. Moore III/Getty Images)
LUBBOCK, TEXAS - SEPTEMBER 10: Quarterback Donovan Smith #7 of the Texas Tech Red Raiders passes the ball during the first half of the game against the Houston Cougars at Jones AT&T Stadium on September 10, 2022 in Lubbock, Texas. (Photo by John E. Moore III/Getty Images)

Wednesday

Georgia State (2-4) at Appalachian State (3-3), 7:30 p.m. ET
Prediction: Appalachian State 30, Georgia State 23


Thursday

Virginia (2-4) at Georgia Tech (3-3), 7:30 p.m. ET
Prediction: Virginia 24, Georgia Tech 20


Friday

Tulsa (2-4) at Temple (2-4), 7:30 p.m. ET
Prediction: Tulsa 28, Temple 24

UAB (4-2) at Western Kentucky (4-3), 8 p.m. ET
Prediction: UAB 27, Western Kentucky 22


Early Saturday

UL Monroe (2-5) at Army (2-4), Noon ET
Prediction: Army 28, UL Monroe 14

Indiana (3-4) at Rutgers (3-3), Noon ET
Prediction: Indiana 24, Rutgers 17

Houston (3-3) at Navy (2-4), Noon ET
Prediction: Houston 34, Navy 28

Akron (1-6) at Kent State (2-5), Noon ET
Prediction: Kent State 44, Akron 21

Duke (4-3) at Miami (3-3), 12:30 p.m. ET
Prediction: Miami 31, Duke 24

Bowling Green (3-4) at Central Michigan (2-5), 1 p.m. ET
Prediction: CMU 26, Bowling Green 24

Eastern Michigan (4-3) at Ball State (4-3), 2 p.m. ET
Prediction: Ball State 34, EMU 31

Northern Illinois (2-5) at Ohio (4-3), 2 p.m. ET
Prediction: NIU 27, Ohio 23

UNLV (4-3) at Notre Dame (3-3), 2:30 p.m. ET
Prediction: Notre Dame 35, UNLV 17

West Virginia (3-3) at Texas Tech (3-3), 3 p.m. ET
Prediction: Texas Tech 31, WVU 30

Rice (3-3) at Louisiana Tech (2-4), 3 p.m. ET
Prediction: Louisiana Tech 32, Rice 29

Rest of the Slate, Part II

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CORVALLIS, OR - SEPTEMBER 24: Quarterback Chance Nolan #10 of the Oregon State Beavers passes the ball to running back Deshaun Fenwick #5 against the USC Trojans at Reser Stadium on September 24, 2022 in Corvallis, Oregon. (Photo by Ali Gradischer/Getty Images)
CORVALLIS, OR - SEPTEMBER 24: Quarterback Chance Nolan #10 of the Oregon State Beavers passes the ball to running back Deshaun Fenwick #5 against the USC Trojans at Reser Stadium on September 24, 2022 in Corvallis, Oregon. (Photo by Ali Gradischer/Getty Images)

Mid-Saturday

BYU (4-3) at Liberty (6-1), 3:30 p.m. ET
Prediction: BYU 34, Liberty 31

Purdue (5-2) at Wisconsin (3-4), 3:30 p.m. ET
Prediction: Wisconsin 27, Purdue 24

Northwestern (1-5) at Maryland (5-2), 3:30 p.m. ET
Prediction: Maryland 28, Northwestern 13

Marshall (3-3) at James Madison (5-1), 3:30 p.m. ET
Prediction: JMU 34, Marshall 20

Western Michigan (2-5) at Miami (Ohio) (3-4), 3:30 p.m. ET
Prediction: Miami 22, WMU 17

Georgia Southern (4-3) at Old Dominion (3-3), 3:30 p.m. ET
Prediction: ODU 31, Georgia Southern 28

Florida International (2-4) at Charlotte (1-6), 3:30 p.m. ET
Prediction: Charlotte 37, FIU 28

Vanderbilt (3-4) at Missouri (2-4), 4 p.m. ET
Prediction: Missouri 29, Vanderbilt 17

Arizona State (2-4) at Stanford (2-4), 4 p.m. ET
Prediction: Arizona State 34, Stanford 27

Hawai'i (2-5) at Colorado State (1-5), 4 p.m. ET
Prediction: Colorado State 28, Hawai'i 24

Florida Atlantic (3-4) at UTEP (3-4), 4 p.m. ET
Prediction: UTEP 27, FAU 21

Arkansas State (2-5) at Louisiana (3-3), 5 p.m. ET
Prediction: Louisiana 30, Arkansas State 24

Southern Miss (3-3) at Texas State (3-4), 5 p.m. ET
Prediction: Southern Miss 26, Texas State 21


Late Saturday

San Jose State (4-2) at New Mexico State (2-5), 6 p.m. ET
Prediction: San Jose State 34, NMSU 17

Fresno State (2-4) at New Mexico (2-5), 6:30 p.m. ET
Prediction: Fresno State 27, New Mexico 14

Texas A&M (3-3) at South Carolina (4-2), 7:30 p.m. ET
Prediction: Texas A&M 24, South Carolina 20

UCF (5-1) at East Carolina (4-3), 7:30 p.m. ET
Prediction: UCF 42, East Carolina 24

Colorado (1-5) at Oregon State (5-2), 8 p.m. ET
Prediction: Oregon State 41, Colorado 14

Pitt (4-2) at Louisville (3-3), 8 p.m. ET
Prediction: Pitt 31, Louisville 28

Utah State (3-4) at Wyoming (4-3), 9:45 p.m. ET
Prediction: Wyoming 20, Utah State 16

Washington (5-2) at Cal (3-3), 10:30 p.m. ET
Prediction: Washington 31, Cal 21

San Diego State (3-3) at Nevada (2-5), 10:30 p.m. ET
Prediction: SDSU 17, Nevada 14

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