NFL Predictions Week 6: Eli Manning and the 3 QBs Who Will Rack Up Picks

It is never easy predicting how many interceptions a quarterback will throw in a game. 

With that being said, some matchups all but guarantee us to see a few interceptions. 

Some signal-callers are just a little more prone to making the big mistake, while some secondaries have a knack for a momentum-shifting pick. 

These three guys have a good chance to throw a few interceptions in Week 6.

Eli Manning, New York Giants

The Buffalo Bills have the most interceptions and total turnovers in the NFL this season (12 INTs, 16 TOs).

It's safe to say that Eli Manning, a turnover-prone quarterback, faces a tough matchup this week.

The Bills will give up a lot of yardage to the Giants and their group of talented wideouts. However, Buffalo should be able to pressure him with their young group of pass-rushers, including Arthur Moats and Kelvin Sheppard. 

Whenever Manning is flustered, he has a tendency to make hurried decisions. These often end with the ball in the other team's hands. 

Against a very opportunistic Bills defense, Manning is bound for a few interceptions.

Rex Grossman, Washington Redskins

The Eagles are essentially in a do-or-die game against their divisional rival, the Redskins. 

Washington should rely on their stable of running backs against Philadelphia's weak run defense. However, in order to stick with Michael Vick and the Eagles offense, they'll need to throw often. 

Grossman has performed admirably this season, but we've seen the old Rex rear his ugly head in the last two weeks. 

With Philadelphia's secondary starting to live up to potential, I expect Grossman to turn the ball over on more than one occasion this weekend.

Matt Moore, Miami Dolphins

Moore gets his first start of the season in prime time against a solid Jets defense. 

Yikes. 

New York's defense hasn't been as dominating this year, but Darrelle Revis and Antonio Cromartie will test Moore and his timing with the Miami receivers all evening. 

Rex Ryan will bring pressure early and often, and Moore is not ready to diagnose the Jets' blitzes and find the hot receiver on a consistent basis.

He's bound to throw a few interceptions.