The team announced that Holliday is dealing with a viral infection and was placed on the DL retroactive to June 25. The Yankees recalled infielder Miguel Andujar from Triple-A to take Holliday's roster spot.
Holliday missed significant time a season ago with a fractured right thumb, but he did flash steady power when healthy.
In 426 plate appearances during the 2016 campaign, Holliday smashed 20 home runs with a .461 slugging percentage and .782 OPS while driving in 62 runs.
In 68 games with the Yankees, Holliday has been terrific with a .262/.366/.511 slash line and 15 home runs in 276 plate appearances.
The 37-year-old will be missed if he's forced to sit for an extended stretch, especially as the disabled list fills up with injured players like Starlin Castro, Greg Bird and Aaron Hicks.
The Yankees still boast a bevy of offensive talent, including Aaron Judge and Brett Gardner, but the lineup's depth looks more tenuous now than it has at any point in 2017.