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NFL Week 2 Live Fantasy Football Start 'Em Sit 'Em Lineup Advice and Latest Injury Updates

Gary Davenport
Sep 20, 2026, updated 5 min ago

Well, that didn't take long.

We're all of one week into the 2026 NFL season, and already the fantasy landscape is shifting rapidly under our feet. We already know that a pair of big-name receivers (Zay Flowers of the Baltimore Ravens and Nico Collins of the Houston Texans) will miss Week 2 due to injuries. Several other prominent pass-catchers are questionable, leaving many fantasy managers in scramble mode well before Sunday's slate even kicks off.

If you're one of those managers patching a hole in your lineup or concerned that you will need to before the games get underway, fear not. Here at Bleacher Report we have you covered, with updated injury news, fantasy insights and player recommendations for Week 2.

Everything is going to be OK.

Or at least that's what I keep telling myself.

Prominent Week 2 Inactives

  • WR Zay Flowers, Baltimore Ravens (hamstring)
  • WR Nico Collins, Houston Texans (hamstring)
  • WR Michael Pittman, Pittsburgh Steelers (foot)

Live Updates

6 Total Posts

Some Good News

Coming off a whopping 10 catches for 182 yards against the Detroit Lions, Chris Olave is questionable for Week 2 with a hamstring injury.

There's always a risk of re-aggravating such an injury. But if Olave is active as expected, he needs to be in fantasy lineups.

The Hard Choices

I face a few decisions like this myself this week. Sadly.

Marks is the floor play here after seeing 10 touches last week. Boutte's role in his second game with the Texans is less certain, but with A.J. Brown on injured reserve he should see a bump in snaps and target share.

Boutte is the play, although he's admittedly a risky one.

Desperation Doubs

Colts Patriots Football

With so many wide receivers banged up, fantasy managers are looking at teams like the Baltimore Ravens, Houston Texans and New England Patriots in the hopes that one of their reserve wideouts might step up in Week 2.

Romeo Doubs of the Patriots is an OK desperation play—he should rebound from last week's goose-egg Sunday against the Pittsburgh Steelers. But there isn't a wide receiver in Houston or Baltimore who is more than a dart-throw.

In fact, the big winners in terms of targets for those two teams are likely veteran tight ends Dalton Schultz and Mark Andrews.

Don't Rush to Start Falcons Pass-Catchers

The last thing fantasy managers of Atlanta Falcons wide receiver Drake London and tight end Kyle Pitts want to have to seriously consider is sitting those players in Week 2--especially with all the injuries at wide receiver.

But the Falcons were the only team in the NFL that didn't reach the red zone last week. Not once. And with Cooper Rush making another start for Atlanta, the fantasy upside has been drained from every Falcon not named Bijan Robinson.

Puka Nacua Iffy for MNF

Well isn't that special?

With Puka Nacua missing practice Friday and Saturday and not playing until Monday night, fantasy managers are in quite the bind. If active, Nacua is a must-start. But those same fantasy managers risk a goose-egg if Nacua sits and they don't have a backup plan at the ready.

Darnell Mooney of the Giants is one fallback option who should be available in most leagues. But after logging just two receptions for 27 yards in the opener, Mooney isn't an especially appealing Plan B.

R.J. Harvey Unlikely to Play

It's not just wide receivers who have been hit by injuries. After a pedestrian opener, R.J. Harvey is unlikely to play Sunday afternoon against the Jaguars.

Harvey's game is a 4:05 PM start, so either have a late-game replacement at the ready or get Harvey out of lineups now.

Rookie Jonah Coleman will see more work with Harvey potentially sidelined.