NFL Week 16 Picks: Predicting the Week's Biggest Losers

The following three teams could find themselves on the wrong side of a blowout in Week 16 of the NFL season:

St. Louis Rams

Another week of healing for Ben Roethlisberger's ankle should do wonders, and James Harrison will return from his one-game suspension. That's good news for the Pittsburgh Steelers, but scary news for the Rams, who travel to Pittsburgh in Week 16.

With the Steelers still knee-deep in a playoff race with the Baltimore Ravens, Pittsburgh needs every win they can get. Don't expect the Steelers to take it easy on a team that hasn't won in six weeks.

Tampa Bay Buccaneers

Few teams have been as disappointing this season as the Buccaneers, and it wouldn't be at all surprising if coach Raheem Morris is let go after the season. It's not going to get any better for either on Sunday against the Carolina Panthers.

The Panthers are fresh off beating a tough Texans team on Sunday, and they have to be licking their chops watching film of the Bucs defense. Cam Newton and the Panthers should run all over that unit. 

Chicago Bears

We haven't seen too many blowouts in the Bears-Packers rivalry as of late, but a Christmas night matchup has the ingredients for one. Chicago has been downright terrible on offense with Caleb Hanie, and the backup options—Josh McCown and Nathan Enderle—aren't exactly pushing Hanie for the starting spot.

The Packers would potentially be vulnerable if the Bears offense was healthy, but Green Bay should have no trouble with a beat up Chicago team at Lambeau Field.