US Open 2013 Schedule: Predictions for Top Seeds on Wednesday

It is still early in the U.S. Open, but after the plethora of quick exits at Wimbledon, fans are paying extra attention to first- and second-round matches in New York.

We've already seen seeded players—No. 14 Jerzy Janowicz, No. 11 Kei Nishikori and No. 15 Nicolas Almagro—fall on the men's side. In the women's draw, former champion No. 11 Samantha Stosur exited, as did No. 12 Kirsten Flipkens, who lost to unseeded, two-time champion Venus Williams.

How will the higher seeds perform on Wednesday? Let's take a look at the schedule and the challenges some of the top seeds will face.

No. 3 Agnieszka Radwanska Rolls—No. 3 Andy Murray and No. 1 Serena Williams Set to Follow Her Lead

Radwanska took the first set of her match with Maria-Teresa Torro-Flor 6-0. Torro-Flor came back to put up a good fight in the second set but still fell 7-5.

Andy Murray and Serena Williams will likely have easy times in their matches as well. Williams is on a mission to right the wrongs from Wimbledon and at the WTA Western and Southern Open. For Williams, winning is the only thing, as she has raised the standards with her stellar play.

She faces unseeded Galina Voskoboeva on Wednesday, and the 28-year-old Russian probably won't fare too well. The two have met once before. Williams won that match 6-2, 6-3 in Rome in 2012.

Murray takes on 33-year-old Frenchman Michael Llodra. The two men have met three times before, with Murray winning all of the matches. Llodra managed to take just one set in all three matches combined.

With Murray taking the next step to become perhaps the best player in the world, it is unlikely Llodra trips him up here.

Most Vulnerable Top-10 Seed: No. 9 Stanislas Wawrinka

Wawrinka battles Radek Stepanek on Wednesday and this could be the spot where the first top-10 men's player exits. Wawrinka has struggled mightily since Wimbledon, when he was upset in the first round by Lleyton Hewitt. 

Since then, he hasn't made it past the second round of any tournament. Stepanek knocked off Fabio Fognini and Almagro in his last two tournaments, so he is capable of competing with the higher-seeded players.

This is definitely a match to watch.

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