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NFL Week 6 Live Fantasy Football Start 'Em Sit 'Em Lineup Advice and Latest Injury Updates

Gary DavenportOct 18, 2026, updated 7 min ago

It seems like only yesterday that the 2026 NFL season was getting underway, but we're already to Week 6โ€”and that means to the fantasy football regular season is just about halfway over.

Things have gone far differently for some than othersโ€”for every team rolling along at 4-1 there's another reeling at 1-4. Never mind all the managers at 3-2 or 2-3 trying to either create positive momentum or maintain it.

No matter their situation, all fantasy managers share something in commonโ€”they are all trying to get a win in Week 6. And we're here to helpโ€”with the injury news, lineup advice and fantasy tips that will help guide them to victory.

Week 6 Inactives

  • QB Lamar Jackson, Baltimore Ravens (Hamstring)
  • QB Jalen Hurts, Philadelphia Eagles (Blood Clotโ€”IR)
  • RB Saquon Barkley, Philadelphia Eagles (Hamstring)
  • RB Jeremiyah Love. Arizona Cardinals (Ankle)
  • RB Kyle Monangai, Chicago Bears (Toe)
  • RB David Montgomery, Houston Texans (Groin)
  • WR Rashee Rice, Kansas City Chiefs (Hamstring)
  • WR Roman Wilson, Pittsburgh Steelers (Finger)
  • WR Deebo Samuel, San Francisco 49ers (Hamstring)
  • RB Jacory Croskey-Merritt, Washington Commanders (Groin)

Live Updates

14 Total Posts

Uncle Rico's Back

Given how effective Jaylen Warren has been as a featured back for the Steelers, it's hard to imagine Rico Dowdle eating into Warren's workload that much against the Buccaneers Sunday.

Still, Dowdle's return is at least a little unsettling for Warren managers.

Colts TE Tyler Warren a Game-Time Decision

Again, late-week injury report adds are bad juju.

Colts tight end Tyler Warren picked up a groin injury in Friday's practice, and it appears he is truly questionable for Sunday's tilt with the Tennessee Titans.

Even if Warren does play, he'll likely be limited. Look elsewhere where possible.

The Mess in Philly

Bengals Eagles Football

Apparently someone broke a mirror in Philadelphia--while walking under a ladder.

The Eagles are getting DeVonta Smith back in Week 6. But with Jalen Hurts on injured reserve, Smith's fantasy value takes a major hit. Dallas Goedert takes a smaller one--it's not difficult to imagine Tanner McKee targeting the tight end quite a bit.

With Saquon Barkley (hamstring) still out, Dameon Pierce will be the Eagles' lead back against a soft Carolina Panthers run defense. But it's hard to get too excited about a back who averaged 1.3 yards per carry last week.

That's Not Dalton Schultz--or Nico Collins

And the first touchdown of Week 6 is a vulture-score.

Here's hoping that isn't a sign of things to come.

Skatteboo-hoo

Between injuries and bye weeks, quite a few fantasy managers have little recourse but to start New York Giants running back Cam Skattebo in Week 6.

But Skattebo's fumbling issues are reportedly going to cost him touches this week against the New Orleans Saints.

Committee backfields make fantasy managers sad.

Frowny-face.

Saint Bernard

Colts Steelers Football

Roman Wilson (finger) and Michael Pittman Jr. (toe) are on IR. DK Metcalf is expected to play but is dinged up. Tight end Pat Freiermuth is questionable.

Germie Bernard could see a hefty target share in Week 6 against the Buccaneers.

This week's biggest waiver darling could make fantasy managers glad they added him--at least for a week.

Welcome Back, Caleb Williams

And fantasy managers of Luther Burden III and Rome Odunze did rejoice.

Fantasy managers with Colston Loveland are still salty.

Been that kind of year.

The Mike Evans Conundrum

Given Mike Evans' long history of playing through nagging injuries, it wouldn't be shocking if he gave it a go Monday night.

But he's battling multiple injuries, and with a lack of available pivots, fantasy managers who wait on Evans could find themselves staring at a zero.

Do you feel lucky?

What Can Brown Do For You?

Fantasy managers are just as happy to see A.J. Brown back in action as the New England Patriots are.

Given the length of his layoff he likely won't play a full snap count, but at the very least he's in the low-end WR2 conversation.

The other Pats wideouts, who were already high-variance, now become that much more so.

Hey, it can't all be good news.

Patriots RB TreVeyon Henderson Expected to Play in Week 6

This is a bit of a surprise--Henderson was originally expected to miss multiple weeks with a high-ankle sprain.

It's also a risky fantasy play--Henderson is capable of taking it to the house any time he touches the ball, but said touches will likely be limited this week.

Browns RB Quinshon Judkins Game-Time Decision

It appears that Quinshon Judkins will try out his balky ankle in pre-game warmups to see if he can go against the Baltimore Ravens.

If Judkins can't go, Jaleel McLaughlin and Audric Estime would carry the rock for a struggling Cleveland run game. McLaughlin would be a so-so, volume-based fantasy "flex" option.

Weather in London

If you're starting any Jaguars or Texans players in Sunday's London game, know that the weather there has become a little, well, London.

Saints WR Chris Olave, RB Alvin Kamara Expected to Play

The good news for fantasy managers is that both wide receiver Chris Olave (illness) and running back Alvin Kamara (back) are expected to be a go Sunday against the New York Giants.

The bad news is that it was also revealed that quarterback Tyler Shough is playing with two broken bones in his left hand.

Steelers "Optimistic" TE Pat Freiermuth Will Play

Getting added to the injury report on Saturday isn't a good sign. But given all the injuries the Steelers have at wide receiver, the team needs Pat Freiermuth out there against the Tampa Bay Buccaneers.

the risk for fantasy managers is that Freiermuth (calf) will see limited snaps. It's a situation best avoided where possible.