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NFL Week 5 Live Fantasy Football Start 'Em Sit 'Em Lineup Advice and Latest Injury Updates

Gary Davenport
Oct 11, 2026, updated just now

It seems like only yesterday that the New England Patriots and Seattle Seahawks were kicking off the 2026 NFL season. But the calendar has turned to October, and we're already a month into the campaign.

It has been a month filled with adversity for fantasy managers. There have been a legitimately historic number of quarterbacks go down, with Lamar Jackson of the Baltimore Ravens joining that list a week ago. The list of banged-up wide receivers reads like War and Peace—which is to say it's long. The running backs and tight ends haven't been spared, either.

Well, we're here to help those fantasy managers overcome that adversity in Week 5--with the injury news, lineup advice and fantasy tips that will either keep the good times rolling or end a depressing early-season skid.

Week 5 Inactives

  • WR Marvin Harrison Jr., Arizona Cardinals (Undisclosed)
  • QB Lamar Jackson, Baltimore Ravens (Ankle)
  • RB Kyle Monangai, Chicago Bears (Toe)
  • WR Jalen Nailor, Las Vegas Raiders (Concussion)
  • RB Breece Hall, New York Jets (Groin)
  • RB Saquon Barkley, Philadelphia Eagles (Hamstring)
  • WR DeVonta Smith, Philadelphia Eagles (Hamstring)
  • WR Michael Pittman Jr., Pittsburgh Steelers (Foot—IR)
  • WR Stefon Diggs, Washington Commanders (Hamstring)

Live Updates

11 Total Posts

Washington in London

Last week against the Cincinnati Bengals, Jaguars wide receiver Parker Wahington had just one catch for seven yards.

Week 5 is off to a better start for the fourth-year veteran.

An Ugly List

Fantasy managers can't afford to wait on D.J. Moore unless they have another option playing Monday night.

The inactives announcement at 11:30 AM will be even more impactful than usual this week.

This is Not Ideal

Given all the injuries at quarterback, many fantasy managers are glad to see Washington's Jayden Daniels back under center in Week 5.

Unfortunately, some apparently believe it's just a matter of time before he winds up on the shelf again.

Sit Commanders WR Terry McLaurin

Even if Washington Commanders wide receiver Terry McLaurin is able to play through his hamstring injury Sunday against the New York Giants, sit him in fantasy leagues wherever possible.

A banged-up wideout on a snap count playing in rotten weather is a disappointment waiting to happen.

Ravens WR Zay Flowers Expected to Play Sunday Night

With the Baltimore Ravens not playing until Sunday night, concerns about the playing status of wide receiver Zay Flowers are amplified.

Flowers will still have to deal with catching passes from a backup quarterback in Tyler Huntley, but he's expected to play through his foot injury against the Atlanta Falcons.

Raiders RB Ashton Jeanty a GTD

It sounds like Raiders RB Ashton Jeanty will try to play Sunday in New England, but he's truly questionable.

Have a Plan B ready to go.

Saints RB Alvin Kamara Expected to Play vs. Vikings

Given the Saints' struggles running the ball and a stout Vikings defense he isn't a great Week 5 play, but New Orleans running back Alvin Kamara (back) is expected to play Sunday.

Patriots RB Rhamondre Stevenson Good to Go

Fantasy managers hoping to see TreVeyon Henderson turned loose Sunday against the Las Vegas Raiders are outta luck.

Rhamondre Stevenson is expected to play through his knee injury.

Colts WR Keenan Allen Expected to Play

With the weather expected to be nasty in Pittsburgh Indianapolis Colts wide receiver Keenan Allen is no more than a so-so "flex" option in Week 5.

But the veteran wideout is expected to be out there despite a groin injury.

Isaias' Impact

The remnants of Hurricane Isaias are fixing to wreak havoc on the early slate of games on the east coast.

Giants at Commanders, Raiders at Patriots, Browns at Jets and Colts at Steelers could all be impacted by rain and/or wind.

Given that those aren't exactly high-octane passing attacks to begin with, the pass-catchers on those teams carry added risk in Week 5.

Chargers WR Ladd McConkey Expected to Sit

With both McConkey (foot) and Quentin Johnston (chest) expected to be sidelined Sunday against the Broncos, Tre' Harris has some plug-and-play appeal against a Denver secondary short Patrick Surtain II and Riley Moss at cornerback.