Indiana Hoosiers Football 2022 Schedule
| Sat, Sep 3 | vsIllinois | 12:00AM UTC | W 20-23 |
| Sun, Sep 11 | vsIdaho | 12:00AM UTC | W 22-35 |
| Sat, Sep 17 | vsWestern Ky. | 4:00PM UTC | W 30-33/OT |
| Sat, Sep 24 | @Cincinnati | 7:30PM UTC | L 24-45 |
| Sat, Oct 1 | @Nebraska | 11:30PM UTC | L 21-35 |
| Sat, Oct 8 | vsMichigan | 4:00PM UTC | L 31-10 |
| Sat, Oct 15 | vsMaryland | 7:30PM UTC | L 38-33 |
| Sat, Oct 22 | @Rutgers | 4:00PM UTC | L 17-24 |
| BYE 😴 |
| Sat, Nov 5 | vsPenn State | 7:30PM UTC | L 45-14 |
| Sat, Nov 12 | @Ohio State | 5:00PM UTC | L 14-56 |
| Sat, Nov 19 | @Michigan St. | 5:00PM UTC | W 39-31/2OT |
| Sat, Nov 26 | vsPurdue | 8:30PM UTC | L 30-16 |
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