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INDIANAPOLIS - NOVEMBER 15:  Quarterback Peyton Manning #18 of the Indianapolis Colts greets Tom Brady #12 of the New England Patriots after the game at Lucas Oil Stadium on November 15, 2009 in Indianapolis, Indiana.  The Colts won the game 35-34. (Photo
INDIANAPOLIS - NOVEMBER 15: Quarterback Peyton Manning #18 of the Indianapolis Colts greets Tom Brady #12 of the New England Patriots after the game at Lucas Oil Stadium on November 15, 2009 in Indianapolis, Indiana. The Colts won the game 35-34. (PhotoJamie Squire/Getty Images

NFL Picks Week 11: Can the Colts Crash the Patriots' Party?

Elliott PohnlNov 17, 2010

NFL Picks Week 11 is here and features a number of possible upsets with a full slate of games on the schedule.

Arguably the most intriguing match-up this week features the Colts traveling to New England to meet the Patriots.

Despite an abundance of injuries, Peyton Manning has engineered Indy to the top of the AFC South.

Meanwhile, New England's young defense dominated Pittsburgh for three quarters Sunday night.

The pupil meets the teacher in Minnesota Sunday, when Aaron Rodgers and the Packers visit Brett Favre and the Vikings.

How much more magic can No. 4 possibly have left in his ailing arm?

Here's a complete look at NFL Week 11 picks.

No. 16: Chicago at Miami

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ARLINGTON, TX - SEPTEMBER 02:  Quarterback Tyler Thigpen #16 of the Miami Dolphins  during a preseason game at Cowboys Stadium on September 2, 2010 in Arlington, Texas.  (Photo by Ronald Martinez/Getty Images)
ARLINGTON, TX - SEPTEMBER 02: Quarterback Tyler Thigpen #16 of the Miami Dolphins during a preseason game at Cowboys Stadium on September 2, 2010 in Arlington, Texas. (Photo by Ronald Martinez/Getty Images)

Why Chicago Could Win: Jay Cutler is finally taking care of the ball, and Mike Martz actually stuck with the run against the Vikings in Week 10.

Why Miami Could Win: Miami's defense has had some nice moments this season, and Tyler Thigpen has more talent than most third-string quarterbacks.

Prediction: Thigpen makes a few big plays in the passing game to spark the Dolphins.

Score: Miami 20, Chicago 16

No. 15: Buffalo at Cincinnati

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ORCHARD PARK, NY - NOVEMBER 14: Ryan Fitzpatrick  #14 of the Buffalo Bills readies to through a pass against the Detroit Lions at Ralph Wilson Stadium on November 14, 2010 in Orchard Park, New York.  (Photo by Rick Stewart/Getty Images)
ORCHARD PARK, NY - NOVEMBER 14: Ryan Fitzpatrick #14 of the Buffalo Bills readies to through a pass against the Detroit Lions at Ralph Wilson Stadium on November 14, 2010 in Orchard Park, New York. (Photo by Rick Stewart/Getty Images)

Why Buffalo Could Win: Ryan Fitzpatrick and the Bills' offense has played very well in the last month and finally managed to eek out a win in Week 10.

Why Cincinnati Could Win: Aside from playing at home, the bumbling Bengals have very little going for them right now.

Prediction: Buffalo torches the Bengals' secondary, making Marvin Lewis' seat even hotter.

Score: Buffalo 27, Cincinnati 24

No. 14: Detroit at Dallas

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ORCHARD PARK, NY - NOVEMBER 14: Shaun Hill #14 of the Detroit Lions throws a pass against the Buffalo Bills  at Ralph Wilson Stadium on November 14, 2010 in Orchard Park, New York.  (Photo by Rick Stewart/Getty Images)
ORCHARD PARK, NY - NOVEMBER 14: Shaun Hill #14 of the Detroit Lions throws a pass against the Buffalo Bills at Ralph Wilson Stadium on November 14, 2010 in Orchard Park, New York. (Photo by Rick Stewart/Getty Images)

Why Detroit Could Win: The Lions haven't had problems moving the ball with Shaun Hill at quarterback, but they need to finish drives with touchdowns.

Playing the Cowboys should help them turn yards into points.

Why Dallas Could Win: Jon Kitna found the fountain of youth Sunday, connecting with his talented receivers early and often.

Detroit's defense is vulnerable, so look for another strong effort from Kitna in Week 11.

Prediction: Antonio Bryant scores at least two touchdowns to lift the Cowboys over the Lions.

Score: Dallas 27, Detroit 17

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No. 13: Washington at Tennessee

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NASHVILLE, TN - OCTOBER 24:  Chris Johnson #28 of the Tennessee Titans runs with the while defended by Asante Samuel #22 of the Philadelphia Eagles at LP Field on October 24, 2010 in Nashville, Tennessee. The Titans won 37-19.  (Photo by Andy Lyons/Getty
NASHVILLE, TN - OCTOBER 24: Chris Johnson #28 of the Tennessee Titans runs with the while defended by Asante Samuel #22 of the Philadelphia Eagles at LP Field on October 24, 2010 in Nashville, Tennessee. The Titans won 37-19. (Photo by Andy Lyons/Getty

Why Washington Could Win: At the moment, the Redskins are hanging on by a thread in the NFC East.  Another loss would basically end any chance of a run towards the postseason.

Why Tennessee Could Win: The Titans can't find consistency on offense, but everybody scores against the Redskins.

Prediction: Chris Johnson has a big game at last and Randy Moss hauls in a touchdown to lead the Titans to a win.

Score: Tennessee 26, Washington 19

No. 12: Arizona at Kansas City

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DENVER - NOVEMBER 14:  Quarterback Matt Cassel #7 of the Kansas City Chiefs heads to the bench against the Denver Bronco at INVESCO Field at Mile High on November 14, 2010 in Denver, Colorado. The Broncos defeated the Chiefs 49-29.  (Photo by Doug Pensing
DENVER - NOVEMBER 14: Quarterback Matt Cassel #7 of the Kansas City Chiefs heads to the bench against the Denver Bronco at INVESCO Field at Mile High on November 14, 2010 in Denver, Colorado. The Broncos defeated the Chiefs 49-29. (Photo by Doug Pensing

Why Arizona Could Win: Even though the Cardinals can't run the ball, the passing game appears to be alive once again with Derek Anderson at quarterback.

Anderson's big arm gives the Cards' a chance against a Chiefs' secondary vulnerable to big plays.

Why Kansas City Could Win: Matt Cassel has finally formed a connection with Dwayne Bowe. 

Look for Kansas City to come out throwing for a change this week.

Prediction: The Chiefs' defense comes to play, leading Todd Haley's team to an easy win.

Score: Kansas City 31, Arizona 16

No. 11: Cleveland at Jacksonville

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CLEVELAND - NOVEMBER 07:  Running back Peyton Hillis #40 of the Cleveland Browns runs the ball against the New England Patriots at Cleveland Browns Stadium on November 7, 2010 in Cleveland, Ohio.  (Photo by Matt Sullivan/Getty Images)
CLEVELAND - NOVEMBER 07: Running back Peyton Hillis #40 of the Cleveland Browns runs the ball against the New England Patriots at Cleveland Browns Stadium on November 7, 2010 in Cleveland, Ohio. (Photo by Matt Sullivan/Getty Images)

Why Cleveland Could Win: Jacksonville is riding high at 5-4, but the Browns are much better than your average 3-6 squad.

Cleveland's defense is good enough to bring the Jaguars back to earth.

Why Jacksonville Could Win: Finally surrounded by weapons on the outside, David Garrard is on pace for his best season.

Don't count the Jags out of the postseason race just yet.

Prediction: The Jaguars are a healthy, and Cleveland won't be able to score too many points on the road.

Garrard throws three touchdowns as Jacksonville wins.

Score: Jacksonville 29, Cleveland 17

No. 10: Baltimore at Carolina

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BALTIMORE, MD - NOVEMBER 7:  Ed Reed #20 of the Baltimore Ravens returns a punt against the Miami Dolphins at M&T Bank Stadium on November 7, 2010 in Baltimore, Maryland. The Ravens defeated the Dolphins 26-10. (Photo by Larry French/Getty Images)
BALTIMORE, MD - NOVEMBER 7: Ed Reed #20 of the Baltimore Ravens returns a punt against the Miami Dolphins at M&T Bank Stadium on November 7, 2010 in Baltimore, Maryland. The Ravens defeated the Dolphins 26-10. (Photo by Larry French/Getty Images)

Why Baltimore Could Win: The Ravens have big-time issues at cornerback, but the Panthers don't have a quarterback.

Why Carolina Could Win: It's been one strange season in the NFL, and Carolina could catch Baltimore off guard with a strong start.

Don't count on it.

Prediction: Ed Reed sparks Baltimore with two interceptions and Joe Flacco does the rest.

Score: Baltimore 35, Carolina 9

No. 9: Oakland at Pittsburgh

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DENVER - OCTOBER 24:  Tight end Zach Miller #80 of the Oakland Raiders celebrates a touchdown reception in the first quarter against the Denver Broncos at INVESCO Field at Mile High on October 24, 2010 in Denver, Colorado. (Photo by Justin Edmonds/Getty I
DENVER - OCTOBER 24: Tight end Zach Miller #80 of the Oakland Raiders celebrates a touchdown reception in the first quarter against the Denver Broncos at INVESCO Field at Mile High on October 24, 2010 in Denver, Colorado. (Photo by Justin Edmonds/Getty I

Why Oakland Could Win: Tom Brady exposed Pittsburgh's corners in Week 10, and Zach Miller could have a big game against the Steelers.

Why Pittsburgh Could Win: The Steelers had one real bad game.  Oakland doesn't have any reliable threats on the outside to exploit the pass defense.

Prediction: The Steelers shut down Jason Campbell and the Raiders' offense to pull off an ugly win.

Score: Pittsburgh 16, Oakland 10

No. 8: Houston at New York Jets

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DETROIT - NOVEMBER 07:  Mark Sanchez #6 of the New York Jets looks to throw a pass during the game against the Detroit Lions at Ford Field on November 7, 2010 in Detroit, Michigan. The Jets defeated the Lions 23-20 in overtime.  (Photo by Leon Halip/Getty
DETROIT - NOVEMBER 07: Mark Sanchez #6 of the New York Jets looks to throw a pass during the game against the Detroit Lions at Ford Field on November 7, 2010 in Detroit, Michigan. The Jets defeated the Lions 23-20 in overtime. (Photo by Leon Halip/Getty

Why Houston Could Win: Assuming Matt Schaub is able to play, the Texans have the weapons to challenge the Jets' secondary.

Why the New York Jets Could Win: Mark Sanchez is licking his chops as he prepares to face Houston's defense.

Prediction: After a slow start, Sanchez hooks up with Santonio Holmes for a long touchdown to spark an easy win.

New York Jets 30, Houston 17

No. 7: Green Bay at Minnesota

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CHICAGO - NOVEMBER 14: Adrian Peterson #28 of the Minnesota Vikings tries to keep his balance as he runs against the Chicago Bears at Soldier Field on November 14, 2010 in Chicago, Illinois. The Bears defeated the Vikings 27-13. (Photo by Jonathan Daniel/
CHICAGO - NOVEMBER 14: Adrian Peterson #28 of the Minnesota Vikings tries to keep his balance as he runs against the Chicago Bears at Soldier Field on November 14, 2010 in Chicago, Illinois. The Bears defeated the Vikings 27-13. (Photo by Jonathan Daniel/

Why Green Bay Could Win: The Vikings' sack party against the Packers last year is all but a memory now.

With Minnesota's pass-rush struggling, Aaron Rodgers appears poised for a huge day.

Why Minnesota Could Win: This will almost certainly be the final meeting between Brett Favre and his former team.

With all eyes focused on Favre, Minnesota turns to Adrian Peterson.

Remember him?

Prediction: Favre is once again running low on weapons in Minnesota.  Meanwhile, Rodgers is getting comfortable with the talent around him.

Rodgers outplays his mentor to lead Green Bay to the win.

Score: Green Bay 28, Minnesota 20

No. 6: Seattle at New Orleans

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CHARLOTTE, NC - NOVEMBER 07:  Drew Brees #9 of the New Orleans Saints against the Carolina Panthers during their game at Bank of America Stadium on November 7, 2010 in Charlotte, North Carolina.  (Photo by Streeter Lecka/Getty Images)
CHARLOTTE, NC - NOVEMBER 07: Drew Brees #9 of the New Orleans Saints against the Carolina Panthers during their game at Bank of America Stadium on November 7, 2010 in Charlotte, North Carolina. (Photo by Streeter Lecka/Getty Images)

Why Seattle Could Win: It's tough to give the fighting Pete Carroll's a chance this week.

If the Saints sleep walk through another home game, the Seahawks could at least be in the game late.

Time to insert the "you never know what could happen" line...

Why New Orleans Could Win: With Pierre Thomas still recovering from his ankle injury, Reggie Bush will be welcomed back in the Bayou. 

Drew Brees is ready for a 350-yard day against that woeful Seahawks' pass defense.

Prediction: Brees takes out his frustration on Seattle's defense, throwing four touchdowns in an easy win.

Score: New Orleans 38, Seattle 16

No. 5: Atlanta at St. Louis

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ATLANTA - NOVEMBER 11:  Quarterback Matt Ryan #2 of the Atlanta Falcons looks to pass against the Baltimore Ravens at Georgia Dome on November 11, 2010 in Atlanta, Georgia.  (Photo by Kevin C. Cox/Getty Images)
ATLANTA - NOVEMBER 11: Quarterback Matt Ryan #2 of the Atlanta Falcons looks to pass against the Baltimore Ravens at Georgia Dome on November 11, 2010 in Atlanta, Georgia. (Photo by Kevin C. Cox/Getty Images)

Why Atlanta Could Win: Roddy White and Matt Ryan are quietly putting up monster numbers for the Falcons.

Atlanta is much better than scrappy St. Louis on both sides of the ball.

Why St. Louis Could Win: This looks like a potential trap-game for the Falcons.  The young Rams are a very dangerous team at home.

Prediction: It won't be easy, but Ryan will do just enough to hang on for a win.

Score: Atlanta 24, St. Louis 23

No. 4: Denver at San Diego

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HOUSTON - NOVEMBER 07:  Quarterback Philips #17 of the San Diego Chargers gives a thumbs up to he bench after a touchdown against the Houston Texans at Reliant Stadium on November 7, 2010 in Houston, Texas.  (Photo by Bob Levey/Getty Images)
HOUSTON - NOVEMBER 07: Quarterback Philips #17 of the San Diego Chargers gives a thumbs up to he bench after a touchdown against the Houston Texans at Reliant Stadium on November 7, 2010 in Houston, Texas. (Photo by Bob Levey/Getty Images)

Why Denver Could Win: The Chargers can throw the ball, but so can the Broncos. 

Kyle Orton could have another huge game in San Diego on Monday night.

Why San Diego Could Win: Philip Rivers has kept the Chargers afloat this season and deserves the MVP award.

After sitting out Week 9, All-Pro Antonio Gates should be back in the lineup.

Prediction: The Broncos shock the world, getting a dominant performance from the passing game and a late touchdown to win.

Score: Denver 34, San Diego 31

No. 3: Tampa Bay at San Francisco

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ATLANTA - NOVEMBER 07:  Quarterback Josh Freeman #5 of the Tampa Bay Buccaneers passes against the Atlanta Falcons at Georgia Dome on November 7, 2010 in Atlanta, Georgia.  (Photo by Kevin C. Cox/Getty Images)
ATLANTA - NOVEMBER 07: Quarterback Josh Freeman #5 of the Tampa Bay Buccaneers passes against the Atlanta Falcons at Georgia Dome on November 7, 2010 in Atlanta, Georgia. (Photo by Kevin C. Cox/Getty Images)

Why Tampa Bay Could Win: For whatever reason, Tampa has proved to be a solid road team this season. 

Points can be a problem for the Bucs, but San Francisco's offense remains a work in progress.

Why San Francisco Could Win: Tampa Bay brings the 30th-ranked run defense to the Bay Area.  Frank Gore should be in line for a monster game on the ground.

Prediction: Tampa Bay takes an early lead, and panic sets in for the Niners. 

Josh Freeman throws a pair of touchdowns to lead the young Bucs.

Score: Tampa Bay 20, San Francisco 13

No. 2: Indianapolis at New England

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INDIANAPOLIS - NOVEMBER 14:  Peyton Manning #18 of the Indianapolis Colts looks to throw a pass during the NFL game against the Cincinnati Bengals at Lucas Oil Stadium on November 14, 2010 in Indianapolis, Indiana. The Colts won 23-17.  (Photo by Andy Lyo
INDIANAPOLIS - NOVEMBER 14: Peyton Manning #18 of the Indianapolis Colts looks to throw a pass during the NFL game against the Cincinnati Bengals at Lucas Oil Stadium on November 14, 2010 in Indianapolis, Indiana. The Colts won 23-17. (Photo by Andy Lyo

Why Indianapolis Could Win: The Colts' offense should finally be at least a little bit healthier in Week 11.

No matter who lines up behind him or on the outside, Peyton Manning could have a nice game against the young Patriots' defense.

Why New England Could Win: The defense is young, but very talented and improving on a weekly basis.

The fighting Belichick's always seem to find a way.

Prediction: At some point, New England will have to make some big plays through the air.  It won't happen in Week 11.

Instead, look for a solid game from BenJarvus Green-Ellis in a Pats' win.

Score: New England 31, Indianapolis 26

No. 1: New York Giants at Philadelphia

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LANDOVER, MD - NOVEMBER 15:  Michael Vick #7 of the Philadelphia Eagles dives over to score a touchdown against the Washington Redskins on November 15, 2010 at FedExField in Landover, Maryland.  (Photo by Chris McGrath/Getty Images)
LANDOVER, MD - NOVEMBER 15: Michael Vick #7 of the Philadelphia Eagles dives over to score a touchdown against the Washington Redskins on November 15, 2010 at FedExField in Landover, Maryland. (Photo by Chris McGrath/Getty Images)

Why the New York Giants Could Win: Every NFL team has had a stinker this season.

With the bad game out of the way, the Giants are lining up for a strong finish thanks to the best offense in the Tom Coughlin era.

Why Philadelphia Could Win: The Michael Vick Experience is back and better than every.  If Vick gets time, he could pick apart a Giants' secondary that was awful in Week 10.

Prediction: New York sets the tone by running the ball against the Eagles, playing keep-away from Vick.

Ahmad Bradshaw and Brandon Jacobs lead the Giants to a close win.

Score: New York Giants 30, Philadelphia Eagles 28

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