Dodgers vs. Padres Betting Odds, Player Props, Picks for Massive NL West Series

The red-hot San Diego Padres come into Dodger Stadium with their latest lead in the NL West standings since September 25, 2010.

All of the momentum is on the side of the Padres, who are on a five-game winning streak and have three losses since August 1.

Even though the Dodgers are on a five-game losing streak, they are a -205 favorite to win the series.

The series price tells us that there's value on the Padres series money line, and in each of the three games.

Friday: Fernando Tatis Over 1.5 Total Bases

Fernando Tatis Jr. owns Clayton Kershaw.

The Padres' superstar has four home runs, five RBIs and a .350 batting average versus the veteran southpaw in 20 career at-bats.

Tatis comes into the series with four two-hit games in his last five and a five-game hitting streak.

Tatis will likely have at least four at-bats from his leadoff spot. He's going up against a pitcher he hits well and one who has allowed at least five hits in each of his last six starts.

Saturday: Dodgers First Five Innings Money Line

Blake Snell had 18 strikeouts in his first 10 innings off the injured list.

Snell only allowed eight hits and three earned runs in those two appearances against the Tampa Bay Rays and Toronto Blue Jays.

Dylan Cease has been more inconsistent in 2025. There's no better example of that than his seven-strikeout innings on June 10 and six earned runs on eight hits on June 16 versus the Dodgers.

Cease owns a 5.52 ERA away from Petco Park as well. He's the ideal pitcher for the Dodgers to take advantage of in the first five innings while Snell cruises.

Sunday: Padres Money Line

The Padres are on a three-game winning streak in Yu Darvish's starts.

The Japanese right-hander has only let up four earned runs in his last 17 innings. San Diego might just need two or three runs to finish off the series.

San Diego has the hitting edge against Kershaw, no matter who opposes Kershaw, and Saturday's matchup is a toss-up.

Tyler Glasnow has been consistent for the Dodgers as well, but his team is 2-4 in his last six starts.

Sunday's money line price will likely be close to even-money, so if you believe in the Padres on Sunday, they are worth the bet on the series money line at +165.