NFL Week 6 Predictions: Can't-Miss Picks and Matchup Guide

Week 6 of the 2013 NFL regular season is upon us, and it's time to predict every game on the schedule and highlight the matchups that will steal the show.

The season is flying by, and several marquee battles this week will have every fan thoroughly entertained. Do not miss a second of the fast-paced action.

All stats and information via NFL.com and ESPN.

Week 6 NFL Schedule and Predicted Winners

Date	Matchup	Predicted Winner	Time (ET)	Watch
Thursday, Oct. 10	NY Giants at Chicago	Chicago Bears	8:25 p.m.	NFL
Sunday, Oct. 13	Cincinnati at Buffalo	Cincinnati Bengals	1 p.m.	CBS
Sunday, Oct. 13	Detroit at Cleveland	Detroit Lions	1 p.m.	Fox
Sunday, Oct. 13	Oakland at Kansas City	Kansas City Chiefs	1 p.m.	CBS
Sunday, Oct. 13	Carolina at Minnesota	Carolina Panthers	1 p.m.	Fox
Sunday, Oct. 13	Pittsburgh at NY Jets	New York Jets	1 p.m.	CBS
Sunday, Oct. 13	Philadelphia at Tampa Bay	Philadelphia Eagles	1 p.m..	Fox
Sunday, Oct. 13	Green Bay at Baltimore	Green Bay Packers	1 p.m.	Fox
Sunday, Oct. 13	St. Louis at Houston	Houston Texans	1 p.m.	Fox
Sunday, Oct. 13	Jacksonville at Denver	Denver Broncos	4:05 p.m.	CBS
Sunday, Oct. 13	Tennessee at Seattle	Seattle Seahawks	4:05 p.m.	CBS
Sunday, Oct. 13	Arizona at San Francisco	San Francisco 49ers	4:25 p.m.	Fox
Sunday, Oct. 13	New Orleans at New England	New Orleans Saints	4:25 p.m.	Fox
Sunday, Oct. 13	Washington at Dallas	Dallas Cowboys	8:30 p.m.	NFL
Monday, Oct. 14	Indianapolis at San Diego	Indianapolis Colts	8:30 p.m.	ESPN

Denver Broncos Over Jacksonville Jaguars

In what could be the most lopsided matchup of the 2013 season, the Jacksonville Jaguars will travel to Denver's Sports Authority Field at Mile High to play the vaunted Broncos in Week 6.

For those not playing along at home, that's the worst team in the league traveling to play the best team. According to RJ Bell of Pregame.com, this mismatch warrants a 28-point spread—the largest in NFL history.

Not only is Jacksonville awful on defense (10th against the pass and 32nd against the run), but the 29th-ranked pass offense and 30th-ranked rushing attack also ensure the Jaguars have no hope of winning this game.

Peyton Manning and the top-ranked Broncos offensive unit will have a monster statistical day, but most of the starters will likely sit most of the second half after mounting enough points in the first half to sustain the team for the rest of the game.

Predicted Final Score: Denver 52, Jacksonville 17

Kansas City Chiefs Over Oakland Raiders

The Kansas City Chiefs are undefeated, and the team will add another win when new head coach Andy Reid leads his players to a dominant win over the Oakland Raiders.

Oakland has turned the ball over to starting quarterback Terrelle Pryor and asked him to lead the team to victory with both his arm and his legs. While that game plan may have worked against the defense of the San Diego Chargers last Sunday night, it will not work against Kansas City.

The Chiefs boast the best all-around defense in the league, allowing just 11.6 points per game and only 312.8 yards of total offense. The pressure from Kansas City's front seven will force Pryor to make mistakes, and the team's fourth-ranked pass defense will capitalize.

Pryor may be the QB of the future, but he will be in serious trouble this week against the Chiefs.

Predicted Final Score: Kansas City 31, Oakland 17

Houston Texans Over St. Louis Rams

The Houston Texans are in serious trouble, but a Week 6 meeting with the St. Louis Rams will be the perfect remedy for many of the offensive woes plaguing the franchise.

Led by the porous decision-making of quarterback Matt Schaub (nine interceptions through five games), the Texans are 2-3 on the season instead of being Super Bowl contenders. With a meeting against the 17th-ranked pass defense and 28th-ranked run defense of St. Louis, Schaub will have a premium opportunity to snap out of his funk.

Add in the fact that the talented Houston defense will be playing with a chip on its shoulder after falling 34-3 to the San Francisco 49ers last week, and the Rams offense doesn't have the firepower to match what the Texans will bring Sunday.

Predicted Final Score: Houston 34, St. Louis 13

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