NFL Picks Week 4: Top Teams That Should Be on Upset Alert

The great thing about the NFL is that any team can win at any time (well, except the Jacksonville Jaguars). This theory will be put to the test in Week 4, as a number of teams are looking at potential upsets.

In Week 3, many were shocked to see teams like the Green Bay Packers, San Francisco 49ers and even the Houston Texans go down.

These types of surprises will continue in the upcoming weekend as top teams have even tougher matchups.

If you are a fan of one of these teams, you should start to prepare for what could be a rough week.

Cincinnati Bengals (at Cleveland Browns)

Although the Browns might not be a better team without Trent Richardson, the squad put together its best performance of the season this week after trading the young running back.

Whether it was the trade or hearing everyone discuss the fact that the Browns had given up on the year, the entire organization reacted in an "us against the world" way with a win over the Minnesota Vikings.

This will give Cleveland confidence heading into its rivalry game against the Cincinnati Bengals. The battle for Ohio is almost always close, and the Browns actually won last season at home 34-24.

Meanwhile, Cincinnati is also coming off a great win, but the team might be feeling too confident after beating the Green Bay Packers and overlook the Browns.

If Joe Haden can slow down A.J. Green, Cleveland has a chance to win for a second week in a row.

San Francisco 49ers (at St. Louis Rams)

Things are set to go from bad to worse in San Francisco. After getting blown out in Seattle, the team responded by losing badly at home against the Indianapolis Colts.

Additionally, the squad is not doing things it used to do well: run the ball and stop the run.

In the last two games, the defense has allowed a combined 351 rushing yards and five rushing touchdowns. On the other side of the ball, starting running back Frank Gore only has 20 carries total in that stretch.

The team is also dealing with key injuries across the board, not to mention that Aldon Smith has left the team to go to rehab, according to CBS Sports' Jason La Canfora:

While the Rams are not playing excellent football right now, they might only need to be average against this struggling divisional rival on Thursday night in prime time.

Seattle Seahawks (at Houston Texans)

It is clear that the Seahawks are very good at CenturyLink Field. However, they still must prove that they can win away from home after finishing 3-5 on the road last season.

Also, it will be difficult for Seattle to move the ball against a Texans defense that ranks second in the league in yards allowed per game.

Of course, the Seahawks have the top-ranked defense in that category, but Houston has a well-balanced offense that is only getting better. The only problem has been mistakes by Matt Schaub, which have led to two interceptions returned for touchdowns in as many weeks.

The veteran quarterback has to be able to cut down on turnovers against the ball-hawking secondary. If he can do that, the Texans have a good chance of pulling off the upset in their home stadium.

Follow Rob Goldberg on Twitter for the latest breaking news and analysis.