MLB Picks: San Francisco Giants vs. Oakland Athletics

San Francisco is 4-6 as road favorites this season. This important to consider when making MLB picks Monday, as the Giants prepare to take on the Oakland Athletics at O.co Coliseum.

Sports bettors will find that the Giants are -120 favorites in the pro baseball odds (courtesy of SBR Forum), while the total sits at 7.5 in the betting market.

Let's take a closer look at this interleague matchup from a betting perspective, while offering up a prediction along the way.

San Francisco Giants

The San Francisco Giants went 4-2 on their most recent six-game homestand. They picked up a 7-3 victory over the Arizona Diamondbacks as -165 favorites on Sunday.

The Giants are 17-9 against the Oakland Athletics since 2008.

Oakland Athletics

The Oakland Athletics return home after a 5-1 road trip, which included a 6-2 victory over the Houston Astros as -169 favorites Sunday.

Since the 2011 season, the Athletics are 24-21 as home underdogs of +100 to +125, with the over coming in 24 of 41 times in that situation.

Prediction

I'm going to recommend that readers back the Oakland Athletics as one of their MLB picks Monday. They've gone 16-5 in their last 21 games following a road trip of seven or more days.

MLB Pick:  Oakland Athletics +105

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