Buffalo Bills vs. Los Angeles Chargers - September 27, 2026

LACou:50.5

Sep 27 @ 01:00pmon FOX

BUF-4.5

Preview

Standings

Highmark StadiumOrchard Park, NY

Indoors

Injuries

D. LeonardDB

Abdomen

QST

L. McConkeyWR

Rib

QST

E. MoldenDB

Hamstring

OUT

T. PipkinsT

Knee

OUT

Injuries

C. BishopS

Knee

QST

T. JohnsonRB

Hamstring

QST

T. SandersDL

Knee

QST

E. OliverDL

Hip

OUT

Live Odds	Spread	O/U	Moneyline
LA Chargers	+4.5 -110	O 50.5 -118	+188
Buffalo Bills	-4.5 -110	U 50.5 -104	-225

Team Comparison

LAC

BUF

0-1

SEASON RECORD

2-0

0-1

RECORD vs. SPREAD

2-0

0-0 (A)

HOME/AWAY

1-0 (H)

L1

TEAM STREAK

W2

League Rankings

LAC

BUF

25th(14)

PTS/G

1st(38.5)

19th(26)

PTS/G ALLOWED

25th(31)

24th(268)

TOTAL YDS/G

1st(427.5)

18th(187)

PASS YDS/G

5th(283)

26th(81)

RUSH YDS/G

7th(144.5)

28th(393)

YDS/G ALLOWED

25th(368)

26th(-2)

TO DIFF

5th(+2)

Season Leaders

LAC

BUF

J. Herbert209 YDS

PASSING YARDS

J. Allen582 YDS

J. Herbert1 TD

PASSING TDS

J. Allen5 TD

O. Hampton43 YDS

RUSHING YARDS

J. Cook192 YDS

O. Hampton1 TD

RUSHING TDS

J. Allen4 TD

L. McConkey82 YDS

RECEIVING YARDS

D. Kincaid225 YDS

L. McConkey1 TD

RECEIVING TDS

J. Palmer2 TD

----

INTERCEPTIONS

----

D. James7 TACKLE

TACKLES

D. Williams9 TACKLE

D. Henley0.5 SACK

SACKS

G. Rousseau4 SACK

Spread

Will BUF win by 5 or more points? Or, will LAC avoid losing by 5 or more points?

LA Chargers

Buffalo Bills

+4.5

-110

-4.5

-110

26%

74%

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Total Points

How many points will both teams score, combined?

LA Chargers

Buffalo Bills

O 50.5

-118

U 50.5

-104

O41%

U59%

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Moneyline

Who will win the game?

LA Chargers

Buffalo Bills

+188

-225

5%

95%

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