Chicago White Sox vs. Cleveland Guardians - June 22, 2026

5

FinalJun 22

6

Recap

Box Score

Plays

Social

Odds

Standings

Scoring Summary

Teams

Guardians logo, Guardians 41-38, 1 0, 2 0, 3 0, 4 0, 5 0, 6 0, 7 3, 8 0, 9 2, R 5, H 8, E 0

White Sox logo, White Sox 40-37, 1 0, 2 1, 3 1, 4 0, 5 0, 6 1, 7 1, 8 0, 9 2, R 6, H 10, E 0

Pitching

WinnerC. Murphy (2-0)

LoserC. Smith (2-1)

Blown SaveS. Domínguez (5)

Scoring

See All

Bot 6Randal Grichuk homers to left field.

Bot 3Andrew Benintendi singles to left center field. Miguel Vargas to third. Sam Antonacci scores.

Bot 2Braden Montgomery doubles to left field. Chase Meidroth scores.

Live Odds	Spread	O/U	Moneyline
Cleveland Guardians	-1.5 +155	O 7.5 -104	-110
Chicago White Sox	+1.5 -188	U 7.5 -118	-106

Guardians vs. White Sox (06/22/2026)

Full highlights from Chicago White Sox' 6-5 win vs. Cleveland Guardians 🎥

Which Team Spends the Most Per Win? 🤑

Breaking down MLB's most and least efficient payrolls

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Guardians Minor League Recap: Akron Lone WinnerMinor league recap for Sunday, June 21st’s games

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Cleveland’s solid series against Astros showcased Guardians' organizational strengthWhile the Guardians dropped their series against the Astros, it showcased just how good their rotation can be.

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Guardians have golden opportunity to slow down upstart White Sox's AL Central pushThe Guardians have a golden opportunity to make a clear statement against the White Sox this week.

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Series Preview: Guardians at White SoxOur old familiar foe

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Early MLB struggles shouldn’t diminish hype around top Guardians prospect Although Kahlil Watson has struggled in his first taste of MLB action, he's still one of the top prospects in the Guardians' system.

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It’s Time for the Guardians’ Front Office to Pull Out All the StopsIt is my professional opinion that now is the time to PANIC

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Guardians floated as landing spot for Mets starter who has disappointed in 2026While Freddy Peralta isn't having the kind of season we're used to seeing, he could still be a great trade target for the Guardians.