NFL Week 10 Picks: Predicting the Week's Biggest Upsets

Every week in the NFL there are at least a couple of games that could be considered upsets. Some are even huge upsets, like the previously winless St. Louis Rams taking down the New Orleans Saints two weeks ago. 

Here are the best candidates for upsets this week.

Carolina Panthers over Tennessee Titans

The Titans felt the sting of a rookie quarterback last week as Andy Dalton led the Bengals back from 10 down, and they now get the most exciting rookie quarterback we've seen since Mike Vick in Cam Newton. Would anyone really be shocked if the Titans dropped their fourth game in their past five games against a 2-6 Panthers team?

Arizona Cardinals over Philadelphia Eagles

In the matter of eight games in 2011, the Eagles have proven two things: They can beat anyone, and they can lose to anyone. Philadelphia is such a talented team, but they can't seem to find any sort of consistency to tie together all the big names. Sunday's game with the Cardinals will have an emotional feel to it, as Kevin Kolb returns to the city that traded him away just three months ago. If he can go on Sunday—and you have to think he will—then won't there be a little revenge on the mind for Kolb? The Cardinals will have to play a near perfect game, but we've seen crazier things happen in the NFL this season.

Cincinnati Bengals over Pittsburgh Steelers

There is going to be a lot of talk this week regarding who the Bengals have beaten in getting to 6-2 and how the Steelers are going to put an end to their unthinkable march to the AFC's top seed through nine weeks. And really, there's no reason not to. The Steelers are the far superior team and will be playing at home against a rookie quarterback. But I'm not sure I'd rule out the Bengals and their chances on Sunday. You don't just fall into six wins in eight tries in the NFL no matter how poor your schedule might be. Winning teams find ways to get it done. The Bengals can certainly go to Pittsburgh and get their seventh win.