NFL Picks Week 5: Score Predictions for All Week 5 Games

Predicting NFL games is easy.

I mean, no teams ever mount comebacks when they're down in the second half, especially underdogs.

In all seriousness, it's never been more difficult predicting games, and all the experts are essentially taking shots in the dark every week. 

After saying all that, here are my most current score predictions for Week 5...

Eagles at Bills

Shoot. Out. Both defenses are weak against the runs and the secondaries are hit or miss. The quarterbacks are comfortable in their systems and the running backs are among the league's best. Buffalo forces more turnovers and gets the edge at home. 

BUF 35 PHI 31

Chiefs at Indianapolis

Dwight Freeney and Robert Mathis will be in the backfield frequently forcing Matt Cassell into some hurried decisions. Curtis Painter will settle down and the Colts running game will lead them to victory. 

IND 17 KC 14

Cardinals at Vikings

I can't envision the Vikings losing a fifth straight game with Adrian Peterson in their backfield. Arizona will see plenty of him and I think Donovan McNabb finally breaks out of his slump. 

MIN 27 ARI 20

Seahawks at Giants

Seattle is traveling cross country to face a far superior club. With New York's pass rush and explosiveness at wide receiver, the Seahawks don't stand a chance. 

NYG 31 SEA 13

Titans at Steelers

A tough one. Big Ben is hobbled but isn't out and the Steelers turn to Isaac Redman to revitalize the run game. I think Matthew Hasselbeck takes a step back and Pittsburgh gets back on track. 

PIT 28 TEN 17

Saints at Panthers 

Another shootout. Both secondaries have been thrashed this season, but the Panthers have the 31st ranked run defense. Expect Sean Payton to exploit Carolina's defense in a variety of ways. Newton should have another big game. 

NO 41 CAR 35

Bengals at Jaguars

The Bengals have one of the league's most aggressive defenses and Andy Dalton is coming into his own as a signal caller. I think Cincinnati applies too much pressure to Blaine Gabbert and wins a low-scoring affair. 

CIN 20 JAC 13

Raiders at Texans

Intriguing game because of Andre Johnson's absence. A great battle of Arian Foster against Darren McFadden. In the end, I think the Texans get to Jason Campbell and run the ball more efficiently and still do enough through the air to win at home. 

HOU 31 OAK 24

Buccaneers at 49ers

Not overly explosive offenses, but they get the job done. I wasn't overly impressed with the Buccaneers on Monday Night and think San Fran's defense will keep LeGarrette Blount in check. 

SF 21 TB 17

Chargers at Broncos

After what we saw Aaron Rodgers do to the Broncos secondary, what makes anyone think Philip Rivers won't be able to turn in a similar performance?

SD 33 DEN 27

Jets at Patriots

Sure to be a cat and mouse game between Rex Ryan and Tom Brady. However, I think Mark Sanchez dooms New York late. 

NE 27 NYJ 20

Packers at Falcons

Aaron Rodgers is playing out of his mind right now and the Falcons secondary really misses Brent Grimes. It should be a high-scoring affair, but the Packers have too many weapons and will create turnovers. 

GB 34 ATL 28

Bears at Lions

I have totally bought into the Lions. They have the best player in football right now, Calvin Johnson and their already dominating defensive line gets rookie Nick Fairley. Scary for Jay Cutler

DET 28 CHI 17