NFL Picks Week 3: Which Teams Will Win by Wide Margins?

Through two weeks of the 2011 NFL season, we've already seen a fair number of blowouts. Week 3 should be no different, as two teams with powerful offenses face two struggling defenses.

The San Diego Chargers have long possessed one of the league's best offensive attacks. This week, they face a Kansas City team that is reeling and ripe to take another beating.

The Chiefs have lost their first two games by a combined score of 89-10 and don't look close to righting the ship. They have lost arguably their best two players for the season, as safety Eric Berry and running back Jamaal Charles both have torn ACLs. Kansas City's offense looks terrible and the defense isn't much better.

The Chargers are coming off a 35-21 loss to the New England Patriots, and only self-inflicted wounds kept them from winning that game. Four turnovers—including a key fourth-quarter fumble by running back Mike Tolbert—held San Diego back.

The Bolts have the league's third-best offense (438.5 yards per game) and the Chiefs don't look like they'll have an answer for it. Expect Philip Rivers to throw all over Kansas City's secondary with Berry out.

In other news, the Pittsburgh Steelers exorcised some of the demons from their 35-7 Week 1 beating at the hands of the Baltimore Ravens this past Sunday. While their 24-0 Week 2 pounding of the Seattle Seahawks had to be satisfying, it couldn't have been enough to make Pittsburgh forget what happened against the Ravens.

The offense has yet to explode, and against an 0-2 Colts team that is struggling mightily on both sides of the ball, expect the Steelers to run out to a big lead early on Sunday night. It will be the perfect opportunity for running back Rashard Mendenhall to really bust loose and finally put together a big afternoon against a weak Indianapolis front seven.

The Chargers and Steelers are both 1-1 right now, and neither squad is happy about it. Expect both of them to have big wins in Week 3.